School of Dentistry, University of Northern Parana-UNOPAR, Londrina, Paraná, Brazil.
Int J Paediatr Dent. 2011 May;21(3):185-91. doi: 10.1111/j.1365-263X.2010.01109.x. Epub 2011 Feb 1.
This study aimed to investigate the dental caries status and salivary properties in 3- to 15-year-old children/adolescents.
The sample was split in two groups: asthma group (AG), composed of 65 patients who attended Public Health Service; asthma-free group (AFG), composed of 65 nonasthmatic children/adolescents recruited in two public schools. Stimulated salivary samples were collected for 3 min. Buffering capacity and pH were ascertained in each salivary sample. A single trained and calibrated examiner (kappa = 0.98) performed the dental caries examination according to WHO criteria.
The AFG showed salivary flow rate (1.10 ± 0.63 mL/min) higher (P = 0.002) than AG (0.80 ± 0.50 mL/min). An inverse relationship was observed between asthma severity and salivary flow rate (Phi coefficient, rφ: 0.79, P = 0.0001). Children with moderate or severe asthma showed an increased risk for reduced salivary flow rate (OR: 17.15, P < 0.001). No association was observed between drug use frequency (P > 0.05) and drug type (P > 0.05) with salivary flow rate. Buffering capacity was similar in both groups. No significant differences were encountered in dental caries experience between AFG and AG groups.
Although asthma can cause reduction in flow rate, the illness did not seem to influence dental caries experience in children with access to proper dental care.
本研究旨在调查 3 至 15 岁儿童/青少年的龋齿状况和唾液特性。
样本分为两组：哮喘组（AG），由 65 名就诊于公共卫生服务的患者组成；非哮喘组（AGF），由两所公立学校招募的 65 名非哮喘儿童/青少年组成。收集 3 分钟的刺激唾液样本。确定每个唾液样本的缓冲能力和 pH 值。一名经过培训和校准的检查员（kappa=0.98）根据世界卫生组织标准进行龋齿检查。
AGF 的唾液流速（1.10±0.63mL/min）高于 AFG（0.80±0.50mL/min）（P=0.002）。哮喘严重程度与唾液流速呈负相关（Phi 系数，rφ：0.79，P=0.0001）。中重度哮喘儿童唾液流速降低的风险增加（OR：17.15，P<0.001）。药物使用频率（P>0.05）和药物类型（P>0.05）与唾液流速之间无关联。两组的缓冲能力相似。AGF 和 AG 组之间的龋齿发生率无显著差异。
尽管哮喘可能导致流速降低，但在接受适当口腔护理的儿童中，该疾病似乎不会影响龋齿的发生。
