Wu Fang-Yi, Liu Jeng-Fen
Pediatric Dentistry, Taichung Veterans General Hospital, Taiwan.
School of Dentistry, National Yang Ming University, Taiwan.
J Dent Sci. 2019 Dec;14(4):413-418. doi: 10.1016/j.jds.2019.08.002. Epub 2019 Sep 16.
BACKGROUND/PURPOSE: Asthma is a common, chronic disease that causes respiratory symptoms in children. Dental caries is also a common chronic disease in the pediatric population. Therefore, the aim of the present study was to investigate the correlation between asthma medications and dental caries among children in Taiwan.
The Taiwan National Health Insurance Research Database was used in this retrospective cohort study to analyze the correlation between asthma and dental caries in children. The prevalence and severity of caries were compared between children with and without asthma. The effects of different asthma medications on dental caries were also compared.
A total of 4601 children with asthma and 4589 children without asthma were included in this study. The caries prevalence of children without asthma was 85.2%, and that of children with asthma was 90.0%. The prevalence of caries in children with asthma was significantly higher than that in children without asthma (P < 0.001). The caries status was categorized into mild, moderate and severe dental caries. The rate of mild dental caries was higher in the children without asthma (35.1%) than in the children with asthma (29.8%). The rate of severe caries was significantly higher in children with asthma (34.3%) than in those without asthma (30.7%). Also, children with asthma using bronchodilators had a higher rate of severe dental caries (39%) than in children without asthma (30.7%).
Children receiving asthma medications had higher dental caries prevalence and higher rate of severe caries than children without asthma.
背景/目的：哮喘是一种常见的慢性疾病，可导致儿童出现呼吸道症状。龋齿也是儿科人群中的一种常见慢性疾病。因此，本研究的目的是调查台湾儿童哮喘药物与龋齿之间的相关性。
本回顾性队列研究使用台湾国民健康保险研究数据库来分析儿童哮喘与龋齿之间的相关性。比较了患哮喘和未患哮喘儿童的龋齿患病率及严重程度。还比较了不同哮喘药物对龋齿的影响。
本研究共纳入4601名哮喘儿童和4589名非哮喘儿童。非哮喘儿童的龋齿患病率为85.2%，哮喘儿童为90.0%。哮喘儿童的龋齿患病率显著高于非哮喘儿童（P<0.001）。龋齿状况分为轻度、中度和重度龋齿。非哮喘儿童的轻度龋齿率（35.1%）高于哮喘儿童（29.8%）。哮喘儿童的重度龋齿率（34.3%）显著高于非哮喘儿童（30.7%）。此外，使用支气管扩张剂的哮喘儿童的重度龋齿率（39%）高于非哮喘儿童（30.7%）。
接受哮喘药物治疗的儿童比未患哮喘的儿童有更高的龋齿患病率和更高的重度龋齿率。
