Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Ill, USA.
J Allergy Clin Immunol. 2011 Feb;127(2):342-50. doi: 10.1016/j.jaci.2010.11.049.
The purpose of this review is to highlight recently published important articles on upper airway diseases and immunotherapy. We review articles on rhinitis, sinusitis, conjunctivitis, and immunotherapy. New insights into epidemiology, pathophysiology, diagnosis, and therapy are described for each of the above diseases. Regarding immunotherapy, we discuss numerous clinical trials on sublingual and subcutaneous immunotherapy, mechanisms of immunotherapy, safety, and use of modified allergens and biological agents for immunotherapy.
本次综述的目的是重点介绍最近发表的有关上呼吸道疾病和免疫疗法的重要文章。我们综述了有关鼻炎、鼻窦炎、结膜炎和免疫疗法的文章。对上述每种疾病的流行病学、病理生理学、诊断和治疗均有新的认识。关于免疫疗法，我们讨论了大量关于舌下和皮下免疫疗法的临床试验、免疫疗法的机制、安全性以及改良过敏原和生物制剂在免疫疗法中的应用。
