Ma W G
School of Stomatology, Fourth Military Medical University, Xi'an.
Zhonghua Kou Qiang Yi Xue Za Zhi. 1990 Jul;25(4):207-9, 251.
The ceramic bovine bones combined with bone morphogenetic protein (BMP) were implanted in the mandibular artificial defects of dogs. Observed by roentgenography, histology (Scanning electronic microscope and light microscope), and radioisotope scanning. The results confirmed that the composite bone possessed superior biocompatibility, osteoinductive and no obvious immunogenic reaction. One year later, the grafted bone and the new bone fused into each other with the histologic structure similar to the host bone. This is a new xenogenic bone graft material which may be used in clinic.
将陶瓷化牛骨与骨形态发生蛋白（BMP）复合后植入犬下颌骨人工缺损处。通过X线摄影、组织学（扫描电子显微镜和光学显微镜）及放射性核素扫描进行观察。结果证实，该复合骨具有优良的生物相容性、骨诱导性且无明显免疫原性反应。1年后，植入骨与新生骨相互融合，组织结构与宿主骨相似。这是一种可用于临床的新型异种骨移植材料。
