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[陶瓷异种骨修复兔下颌骨缺损的实验研究]

[An experimental study on ceramic xenogenic bone in reconstructing defects of the mandible in rabbits].

作者信息

Ma W G

出版信息

Zhonghua Kou Qiang Yi Xue Za Zhi. 1989 Jul;24(4):212-4, 255.

PMID:2517094
Abstract

In the experiment, fresh bovine bone was chemically defatted and deproteinized, and sintered by high temperature (which is called ceramic bovine bone). The ceramic bovine bone was implanted in the artificial defects of mandibles of 25 rabbits. Observing by X-ray, histology, tetracycline and calcein yellow-green fluorescence double labelling and scanning electric-microscope, we proved that the ceramic bovine bone possessed good bone affinity, promoting new bone calcification, no immunogenic reaction, and was not absorbed within three months. It is a good bone graft material which may be used in clinic.

摘要

在实验中,将新鲜牛骨进行化学脱脂和脱蛋白处理,然后高温烧结(称为陶瓷化牛骨)。将陶瓷化牛骨植入25只家兔下颌骨的人工缺损处。通过X射线、组织学、四环素和钙黄绿素黄绿荧光双标记以及扫描电镜观察,我们证明陶瓷化牛骨具有良好的骨亲和性,能促进新骨钙化,无免疫原性反应,且在三个月内不被吸收。它是一种可用于临床的良好骨移植材料。

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