Ma W G
Zhonghua Kou Qiang Yi Xue Za Zhi. 1989 Jul;24(4):212-4, 255.
In the experiment, fresh bovine bone was chemically defatted and deproteinized, and sintered by high temperature (which is called ceramic bovine bone). The ceramic bovine bone was implanted in the artificial defects of mandibles of 25 rabbits. Observing by X-ray, histology, tetracycline and calcein yellow-green fluorescence double labelling and scanning electric-microscope, we proved that the ceramic bovine bone possessed good bone affinity, promoting new bone calcification, no immunogenic reaction, and was not absorbed within three months. It is a good bone graft material which may be used in clinic.
在实验中,将新鲜牛骨进行化学脱脂和脱蛋白处理,然后高温烧结(称为陶瓷化牛骨)。将陶瓷化牛骨植入25只家兔下颌骨的人工缺损处。通过X射线、组织学、四环素和钙黄绿素黄绿荧光双标记以及扫描电镜观察,我们证明陶瓷化牛骨具有良好的骨亲和性,能促进新骨钙化,无免疫原性反应,且在三个月内不被吸收。它是一种可用于临床的良好骨移植材料。