Department of Obstetrics and Gynaecology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong.
Hong Kong Med J. 2011 Feb;17(1):5-10.
To compare the effects of laparoscopic ovarian drilling in treating infertile polycystic ovarian syndrome in patients with and without metabolic syndrome.
Retrospective review.
A university-affiliated hospital in Hong Kong.
A total of 89 infertile anovulatory polycystic ovarian syndrome patients, who underwent laparoscopic ovarian drilling with completed metabolic screening and seen over a 5-year period from 2002 to 2007.
The clinical, hormonal, and metabolic characteristics as well as spontaneous ovulation rates, reproductive outcomes, and diabetes risks during pregnancy observed after laparoscopic ovarian drilling.
Approximately one fifth (21%) of polycystic ovarian syndrome patients had the metabolic syndrome. There were no differences in spontaneous ovulation rates (68% vs 61%, P=0.76), cumulative pregnancy rates (68% vs 61%, P=0.77), and diabetes risks during pregnancy (64% vs 42%, P=0.13) between patients with and without metabolic syndrome.
Laparoscopic ovarian drilling was equally effective in inducing ovulation in polycystic ovarian syndrome patients with metabolic syndrome. Thus, patients with metabolic syndrome should not be precluded from laparoscopic ovarian drilling, which has the additional advantage of enabling full tubo-peritoneal assessment at the same time.
比较腹腔镜卵巢打孔术治疗伴有和不伴有代谢综合征的不孕多囊卵巢综合征患者的效果。
回顾性研究。
中国香港一家大学附属医院。
2002 年至 2007 年间共 89 名接受腹腔镜卵巢打孔术且已完成代谢筛查的不孕无排卵多囊卵巢综合征患者。
腹腔镜卵巢打孔术后的临床、激素和代谢特征以及自发排卵率、生殖结局和妊娠期间的糖尿病风险。
大约五分之一（21%）的多囊卵巢综合征患者患有代谢综合征。伴有和不伴有代谢综合征的患者的自发排卵率（68%比 61%，P=0.76）、累积妊娠率（68%比 61%，P=0.77）和妊娠期间的糖尿病风险（64%比 42%，P=0.13）均无差异。
腹腔镜卵巢打孔术同样能有效诱导代谢综合征的多囊卵巢综合征患者排卵。因此，不应排除代谢综合征患者进行腹腔镜卵巢打孔术，该手术还具有同时进行全面输卵管-腹膜评估的额外优势。
