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肾源性系统性纤维化

Nephrogenic systemic fibrosis.

作者信息

Braverman Irwin M, Cowper Shawn

机构信息

Department of Dermatology, Yale Medical School New Haven, CT 06520 USA.

出版信息

F1000 Med Rep. 2010 Nov 24;2:84. doi: 10.3410/M2-84.

DOI:10.3410/M2-84
PMID:21283650
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3026615/
Abstract

Nephrogenic systemic fibrosis, initially called nephrogenic fibrosing dermopathy, has been strongly linked to exposure to gadolinium-based contrast media used in magnetic resonance imaging in patients with renal insufficiency. This review discusses recent advances in our understanding of the pathophysiology and clinical approach to patients with chronic kidney disease who require diagnostic imaging with gadolinium-based contrast media.

摘要

肾源性系统性纤维化,最初称为肾源性纤维性皮肤病,已被证实与肾功能不全患者在磁共振成像中使用钆基造影剂密切相关。本综述讨论了我们对需要使用钆基造影剂进行诊断成像的慢性肾脏病患者的病理生理学和临床治疗方法的最新认识进展。

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Nephrogenic systemic fibrosis.肾源性系统性纤维化
F1000 Med Rep. 2010 Nov 24;2:84. doi: 10.3410/M2-84.
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Contemporary applications and limitations of magnetic resonance imaging contrast materials.当代磁共振成像对比剂的应用及局限性。
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Gadolinium-enhanced magnetic resonance imaging, renal failure and nephrogenic systemic fibrosis/nephrogenic fibrosing dermopathy.钆增强磁共振成像、肾衰竭与肾源性系统性纤维化/肾源性纤维性皮肤病
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本文引用的文献

1
Synchrotron X-ray analyses demonstrate phosphate-bound gadolinium in skin in nephrogenic systemic fibrosis.同步加速器 X 射线分析表明,肾源性系统性纤维化皮肤中有与磷酸盐结合的钆。
Br J Dermatol. 2010 Nov;163(5):1077-81. doi: 10.1111/j.1365-2133.2010.09918.x.
2
Nephrogenic systemic fibrosis: incidence, associations, and effect of risk factor assessment--report of 33 cases.肾源性系统性纤维化:发病率、关联因素及风险因素评估的影响——33例报告
Radiology. 2009 Feb;250(2):371-7. doi: 10.1148/radiol.2502080498.
3
Gadodiamide contrast agent 'activates' fibroblasts: a possible cause of nephrogenic systemic fibrosis.钆双胺造影剂“激活”成纤维细胞:肾源性系统性纤维化的一个可能原因。
J Pathol. 2008 Apr;214(5):584-93. doi: 10.1002/path.2311.
4
The impact of NSF on the care of patients with kidney disease.NSF对肾病患者护理的影响。
J Am Coll Radiol. 2008 Jan;5(1):45-52. doi: 10.1016/j.jacr.2007.08.018.
5
Circulating fibrocytes: cellular basis for NSF.循环纤维细胞: NSF的细胞基础
J Am Coll Radiol. 2008 Jan;5(1):36-9. doi: 10.1016/j.jacr.2007.08.016.
6
Gadolinium is quantifiable within the tissue of patients with nephrogenic systemic fibrosis.钆在患有肾源性系统性纤维化的患者组织中是可量化的。
J Am Acad Dermatol. 2007 Apr;56(4):710-2. doi: 10.1016/j.jaad.2007.01.022. Epub 2007 Feb 7.
7
Gadolinium-based MR contrast agents and nephrogenic systemic fibrosis.钆基磁共振造影剂与肾源性系统性纤维化
Radiology. 2007 Mar;242(3):647-9. doi: 10.1148/radiol.2423061640. Epub 2007 Jan 9.
8
Nephrogenic fibrosing dermopathy.
Am J Dermatopathol. 2001 Oct;23(5):383-93. doi: 10.1097/00000372-200110000-00001.