右美托咪定用于疼痛控制。
Use of dexmedetomidine for pain control.
作者信息
Grosu Irina, Lavand'homme Patricia
机构信息
Department of Anesthesiology, Saint-Luc Hospital Medical School, Université Catholique de Louvain Avenue Hippocrate 10-1821, B-1200 Brussels Belgium.
出版信息
F1000 Med Rep. 2010 Dec 17;2:90. doi: 10.3410/M2-90.
Abstract
For many years, clonidine, an α2-adrenergic receptor (α2-AR) agonist, has been widely used as an analgesic adjuvant in perioperative conditions and pain therapy. Dexmedetomidine (DMET) is currently the most potent α2-AR agonist available and was first approved as a sedative agent for use in the intensive care unit. However, DMET has recently been investigated for its analgesic effects and has the potential to become an alternative to clonidine.
摘要
多年来，可乐定，一种α2肾上腺素能受体（α2-AR）激动剂，已被广泛用作围手术期和疼痛治疗中的镇痛辅助药物。右美托咪定（DMET）是目前可用的最有效的α2-AR激动剂，最初被批准用作重症监护病房的镇静剂。然而，最近对DMET的镇痛作用进行了研究，它有潜力成为可乐定的替代品。
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