Department of Hepatobiliary Surgery, Shanghai Tenth People Hospital, Tongji University School of Medicine, Shanghai, China.
J Surg Oncol. 2011 Jun;103(8):807-12. doi: 10.1002/jso.21814. Epub 2011 Jan 31.
Hepatic angiomyolipoma is more frequently encountered in clinical practice, its diagnosis is difficult, its treatment remains controversial. We review a single-center experience in the treatment of hepatic angiomyolipoma.
The clinical data of 79 patients with hepatic angiomyolipoma treated at the authors' institute between January 1992 and December 2006 were retrospectively reviewed.
During a period of 15 years, a total of 79 patients with hepatic angiomyolipoma underwent liver resection at our hospital. There are 58 women and 21 men. The tumor size varied from 1 to 25 cm in diameter (6.1 ± 4.08). Fifty-four patients (68%) were asymptomatic. Accurate preoperative diagnosis was made in 41 patients (52%). Tumors less than 6 cm in size were more frequently misdiagnosed. Spontaneous rupture occurred in one patient. One patient had tumor recurrence 6 years after the surgery, and died of the disease 1 year later. Symptom relief was achieved in 92% of the symptomatic patients. Median survival was 90 months (90.12 ± 30.84).
Hepatic angiomyolipoma poses a diagnostic challenge clinically and radiologically. Surgical resection is a safe and effective treatment option. It is important to realize the potential of malignant transformation and risk of rupture as life-threatening complications.
肝血管平滑肌脂肪瘤在临床上较为常见，其诊断困难，治疗仍存在争议。我们回顾了单中心治疗肝血管平滑肌脂肪瘤的经验。
回顾性分析 1992 年 1 月至 2006 年 12 月作者所在医院治疗的 79 例肝血管平滑肌脂肪瘤患者的临床资料。
15 年间，我院共对 79 例肝血管平滑肌脂肪瘤患者行肝切除术，其中女性 58 例，男性 21 例，肿瘤直径 1～25cm，平均（6.1±4.08）cm。54 例（68%）患者无症状，41 例（52%）术前诊断准确。直径＜6cm 的肿瘤更容易误诊。1 例患者发生自发性破裂。1 例患者术后 6 年复发，1 年后死于该病。92%的有症状患者症状缓解。中位生存时间为 90 个月（90.12±30.84）。
肝血管平滑肌脂肪瘤在临床上和影像学上具有诊断挑战性。手术切除是一种安全有效的治疗选择。需要认识到恶性转化和破裂的潜在风险，因为这是危及生命的并发症。
