Center for Anxiety and Traumatic Stress Disorders and Complicated Grief Program, Massachusetts General Hospital, Boston, Massachusetts 02114, USA.
Depress Anxiety. 2011 Feb;28(2):118-26. doi: 10.1002/da.20775. Epub 2010 Dec 15.
Complicated Grief (CG) is under consideration as a new diagnosis in DSM5. We sought to add empirical support to the current dialogue by examining the commonly used Inventory of Complicated Grief (ICG) scale completed by 782 bereaved individuals.
We employed IRT analyses, factor analyses, and sensitivity and specificity analyses utilizing our full sample (n = 782), and also compared confirmed CG cases (n = 288) to noncases (n = 377). Confirmed CG cases were defined as individuals bereaved at least 6 months who were seeking care for CG, had an ICG ≥ 30, and received a structured clinical interview for CG by a certified clinician confirming CG as their primary illness. Noncases were bereaved individuals who did not present with CG as a primary complaint (including those with depression, bipolar disorder, anxiety disorders, and controls) and had an ICG<25.
IRT analyses provided guidance about the most informative individual items and their association with CG severity. Factor analyses demonstrated a single factor solution when the full sample was considered, but within CG cases, six symptom clusters emerged: (1) yearning and preoccupation with the deceased, (2) anger and bitterness, (3) shock and disbelief, (4) estrangement from others, (5) hallucinations of the deceased, and (6) behavior change, including avoidance and proximity seeking. The presence of at least one symptom from three different symptom clusters optimized sensitivity (94.8%) and specificity (98.1%).
These data, derived from a diverse and predominantly clinical help seeking population, add an important perspective to existing suggestions for DSM5 criteria for CG.
复杂型悲伤(Complicated Grief,CG)被考虑作为 DSM5 中的一个新诊断。我们试图通过检查 782 名丧亲者完成的常用《复杂型悲伤量表》(Inventory of Complicated Grief,ICG),为当前的对话提供实证支持。
我们利用全样本(n=782)进行了 IRT 分析、因子分析以及敏感性和特异性分析,同时将确诊 CG 病例(n=288)与非病例(n=377)进行了比较。确诊 CG 病例的定义为至少丧亲 6 个月,因 CG 寻求治疗、ICG≥30,且由经过认证的临床医生进行的 CG 结构化临床访谈,确定 CG 是他们的主要疾病。非病例为丧亲者,但不以 CG 作为主要主诉(包括患有抑郁症、双相情感障碍、焦虑症和对照组),且 ICG<25。
IRT 分析为最具信息量的个体项目及其与 CG 严重程度的关联提供了指导。因子分析表明,当考虑全样本时,存在一个单一的因素解决方案,但在 CG 病例中,出现了六个症状群:(1)对死者的渴望和专注,(2)愤怒和痛苦,(3)震惊和难以置信,(4)与他人疏远,(5)死者的幻觉,(6)行为改变,包括回避和接近寻求。至少有三个不同症状群的一个症状存在,可以优化敏感性(94.8%)和特异性(98.1%)。
这些数据源自多样化且主要是寻求临床帮助的人群,为 DSM5 中 CG 标准的现有建议提供了重要视角。