综述：老年人谵妄——全面综述。
Review: delirium in the elderly: a comprehensive review.
机构信息
BJC Healthcare System, Farmington, MO, USA.
出版信息
Am J Alzheimers Dis Other Demen. 2011 Mar;26(2):97-109. doi: 10.1177/1533317510397331. Epub 2011 Jan 31.
Abstract
Delirium is a common neuropsychiatric syndrome in the elderly characterized by concurrent impairments in cognition and behaviors. The etiologies for delirium are often multifactorial and are due to underlying medical illnesses and/or due to medication effect. The diagnosis of delirium is often missed in elderly patients and this condition may be mislabeled as depression or dementia. Untreated, delirium can have devastating consequences in the elderly with high rates of morbidity and mortality. Available evidence indicates that early detection, reduction of risk factors, and better management of this condition can decrease its morbidity rates. In this review, we discuss the etiology, neurobiology, diagnosis, prevention, and treatments for this potentially lethal condition in the elderly.
摘要
谵妄是一种常见的老年神经精神综合征，其特征是认知和行为同时受损。谵妄的病因通常是多因素的，是由于潜在的疾病和/或药物作用引起的。老年患者中谵妄的诊断常常被遗漏，这种情况可能被误诊为抑郁症或痴呆症。未经治疗，谵妄可能对老年人造成严重后果，发病率和死亡率高。现有证据表明，早期发现、减少危险因素和更好地管理这种情况可以降低发病率。在这篇综述中，我们讨论了这种潜在致命疾病在老年人中的病因、神经生物学、诊断、预防和治疗。
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