Department of Internal Medicine, Armed Forces Capital Hospital, Seongnam, Korea.
J Korean Med Sci. 2011 Feb;26(2):201-6. doi: 10.3346/jkms.2011.26.2.201. Epub 2011 Jan 24.
The objective of this study was to evaluate the prevalence of asthma, allergic rhinitis, and atopic dermatitis, as well as the risk factors of wheezing among young adults in the Korean military. Young military conscripts in five areas completed a modified International Study of Asthma and Allergies in Childhood (ISAAC) questionnaire. For subjects with current wheeze in one sample area, baseline spirometry and bronchodilator response were measured. For subjects without a significant response to bronchodilator (improvement in FEV1 of more than 200 mL and 12%), methacholine challenge tests (MCT) were also performed. Of 3,359 subjects that completed the questionnaire, 354 (10.5%) had current wheeze, 471 (14.0%) had current allergic rhinitis, and 326 (9.7%) had current eczema. Current wheeze was associated with family history of allergic disease, overweight, current smoking, allergic rhinitis, and atopic dermatitis. Of 36 subjects with current wheeze who underwent PFT with or without MCT in the Anyang area, 24 (66.7%) were confirmed to have current asthma. In conclusion, the prevalence of allergic disease in young adults of Korean military is not low, and the risk factors of wheezing include family history of allergic disease, overweight, current smoking, allergic rhinitis, and atopic dermatitis.
本研究旨在评估韩国军队中年轻人哮喘、过敏性鼻炎和特应性皮炎的患病率，以及喘息的危险因素。五个地区的年轻应征入伍者完成了改良的国际儿童哮喘和过敏研究（ISAAC）问卷。对于一个样本区域中当前有喘息的受试者，测量了基线肺功能和支气管扩张剂反应。对于对支气管扩张剂没有明显反应（FEV1 改善超过 200 毫升和 12%）的受试者，还进行了乙酰甲胆碱挑战测试（MCT）。在完成问卷的 3359 名受试者中，354 名（10.5%）有当前喘息，471 名（14.0%）有当前过敏性鼻炎，326 名（9.7%）有当前湿疹。当前喘息与过敏性疾病家族史、超重、当前吸烟、过敏性鼻炎和特应性皮炎有关。在安阳地区接受或不接受 MCT 的肺功能测试的 36 名当前喘息的受试者中，有 24 名（66.7%）被确诊为当前哮喘。总之，韩国军队中年轻人过敏疾病的患病率不低，喘息的危险因素包括过敏性疾病家族史、超重、当前吸烟、过敏性鼻炎和特应性皮炎。
