Department of Anesthesiology and Pain Medicine, Samsung Medical Center, Seoul, Korea.
Korean J Anesthesiol. 2010 Dec;59 Suppl(Suppl):S128-32. doi: 10.4097/kjae.2010.59.S.S128. Epub 2010 Dec 31.
We present two cases of dynamic left ventricular outflow tract obstruction in 2 patients who were undergoing living donor liver transplantation. On the preoperative transthoracic echocardiography, the first patient showed normal ventricular function and a normal wall thickness, but severe hemodynamic deterioration developed during the anhepatic period and this was further aggravated after reperfusion in spite of volume resuscitation and catecholamine therapy. Intraoperative transesophageal echocardiography revealed the systolic anterior motion of the mitral valve leaflet together with left ventricular outflow tract obstruction. The second patient showed left ventricular hypertrophy with left ventricular outflow tract obstruction on the preoperative echocardiography. Intraoperative transesophageal echocardiography was used to guide fluid administration and the hemodynamic management throughout the procedure and a temporary portocaval shunt was established to mitigate the venous pooling during the anhepatic period. The purpose of this report is to emphasize the clinical significance of dynamic left ventricular outflow tract obstruction in patients who are undergoing living donor liver transplantation and the role of intraoperative echocardiography to detect and manage it.
我们报告了 2 例活体肝移植患者发生的左心室流出道动力性梗阻。术前经胸超声心动图显示,第 1 例患者心室功能和壁厚度正常,但在无肝期出现严重血流动力学恶化,尽管进行了容量复苏和儿茶酚胺治疗,但再灌注后情况进一步加重。术中经食管超声心动图显示二尖瓣前叶收缩期前向运动伴左心室流出道梗阻。第 2 例患者术前超声心动图显示左心室肥厚伴左心室流出道梗阻。术中经食管超声心动图用于指导整个手术过程中的液体管理和血流动力学管理,并建立临时门腔分流以减轻无肝期的静脉淤积。本报告的目的是强调活体肝移植患者发生左心室流出道动力性梗阻的临床意义,以及术中超声心动图在检测和处理方面的作用。