Kirillova I A, Novikova I V, Bragina Z N
Arkh Patol. 1990;52(12):14-9.
Total incidence of the alimentary system defects was 1.05 +/- 0.12% in the non-selected material of medical abortions performed at 5-12 weeks of the intrauterine development. Atresia and stenosis of the duodenum are described for the first time in the embryos of the above age, the possibility of differential diagnosis between physiological and pathological atresia is established. The connection between the ducts of the ring-like head of pancreas and ductus choledochus is observed thus confirming the hypothesis of the additional pancreatic part developing from the ventral anlage. Diagnosis of Mekkel's diverticulum became possible beginning from stage 17. The existence of atresia, stenosis and gastro-intestinal tract doubling in the embryos of the above age indicate that at least some of these defects are not connected with a secondary damage of the intestinal tube due to circulation disturbances, recanalization or inflammation but represent a primary developmental anomaly arising in the early ontogenesis.
在宫内发育5至12周进行的非选择性人工流产材料中，消化系统缺陷的总发生率为1.05±0.12%。首次在上述年龄的胚胎中描述了十二指肠闭锁和狭窄，确立了生理性和病理性闭锁之间进行鉴别诊断的可能性。观察到胰腺环状头部导管与胆总管之间的连接，从而证实了胰腺额外部分由腹侧原基发育而来的假说。从第17阶段开始就有可能诊断梅克尔憩室。上述年龄胚胎中存在闭锁、狭窄和胃肠道重复表明，这些缺陷中至少有一些并非由于循环障碍、再通或炎症导致肠管继发性损伤，而是代表早期个体发育中出现的原发性发育异常。
