Popov A V, Kuznetsov A S, Lozovskiĭ V T
Vopr Med Khim. 1978 Sep-Oct;24(5):670-5.
Lipoprotein complexes were studied in intact parts of human aorta as well as in areas of aorta impaired with atherosclerosis. The arterial walls contained particles, which were similar to pre-beta and beta-lipoproteins as evidenced by immunological properties and by size. At the same time, lipoproteins of the vascular walls differed distinctly from those of blood serum because these former lipoproteins possesed altered electrophoretic mobilities in acetyl cellulose, contained glycosamineglycans, exhibited lower rate of flotation in salt-free solution as compared with the salt-containing solution under conditions of analytical ultracentrifugation. The data obtained suggest that the lipoproteins formed complexes with glycosamineglucans in vascular walls.
脂蛋白复合物在人体主动脉的完整部分以及动脉粥样硬化受损的主动脉区域进行了研究。动脉壁中含有颗粒，从免疫学特性和大小来看，这些颗粒类似于前β脂蛋白和β脂蛋白。与此同时，血管壁的脂蛋白与血清脂蛋白明显不同，因为这些前者脂蛋白在乙酰纤维素中具有改变的电泳迁移率，含有糖胺聚糖，在分析超速离心条件下，与含盐溶液相比，在无盐溶液中的漂浮率较低。所获得的数据表明，脂蛋白在血管壁中与糖胺聚糖形成了复合物。
