Mateos V, Garcia-Monco J C, Gomez-Beldarrain M, Armengol-Bertolin S, Larios C
Hospital Universitario Central de Asturias, 33006 Oviedo, Espana.
Rev Neurol. 2011 Feb 1;52(3):131-8.
Migraine has recently been associated to certain personality profiles and styles of coping.
To explore the association between personality factors, disability and the therapeutic management of migraine.
We conducted an epidemiological, cross-sectional, multi-centre study with patients with migraine visiting a neurology unit for the first time. Socio-demographic and clinical data were collected about the patients. The NEO-FFI (Neuroticism-Extraversion-Openness Five-Factor Inventory) was used to evaluate personality factors; the degree of disability was evaluated using the Headache Impact Test (HIT-6) and the number of lost workday equivalents (LWDE) was measured. Bivariate logistic regression analyses were also performed.
A total of 736 patients were recruited, of whom 700 were suitable for inclusion in the analysis (75.6% females; mean age: 35.5 ± 11.5 years). In all, 68.9% presented migraine without aura, 1-4 seizures/month (66.7%) and of moderate intensity (58.1%). A total of 76.1% of patients had severe disability according to the HIT-6. Of the 554 active patients, the mean number of lost workday equivalents in the previous three months was 6.8 ± 8.2. Patients showed greater emotional instability than the general population and they scored lower on extraversion, openness, agreeableness and conscientiousness. All the patients were being treated for their migraine: 47.3% by means of stepped treatment between seizures; 39.9% intra-seizures, and stratified in only 12.9%.
This study confirms the impact of migraine in terms of disability and in terms of loss of labour output, together with its association with personality factors.
偏头痛最近被认为与某些人格特征和应对方式有关。
探讨人格因素、残疾与偏头痛治疗管理之间的关联。
我们对首次到神经内科就诊的偏头痛患者进行了一项流行病学、横断面、多中心研究。收集了患者的社会人口学和临床数据。使用NEO-FFI（神经质-外向性-开放性五因素问卷）评估人格因素；使用头痛影响测试（HIT-6）评估残疾程度，并测量损失工作日当量（LWDE）的数量。还进行了双变量逻辑回归分析。
共招募了736名患者，其中700名适合纳入分析（女性占75.6%；平均年龄：35.5±11.5岁）。总体而言，68.9%的患者表现为无先兆偏头痛，每月发作1-4次（66.7%），强度为中度（58.1%）。根据HIT-6，共有76.1%的患者有严重残疾。在554名活动患者中，前三个月损失工作日当量的平均数为6.8±8.2。患者表现出比一般人群更大的情绪不稳定性，在外向性、开放性、宜人性和尽责性方面得分较低。所有患者都在接受偏头痛治疗：47.3%采用发作间期逐步治疗；39.9%采用发作期治疗，仅12.9%采用分层治疗。
本研究证实了偏头痛在残疾和劳动力产出损失方面的影响，以及其与人格因素的关联。
