Zlotogora Joël, Haklai Ziona, Rotem Naama, Georgi Moriah, Rubin Lisa
Ministry of Health, Jerusalem, Israel.
Isr Med Assoc J. 2010 Sep;12(9):539-42.
Ultrasound examination of the fetus enables diagnosis of many major malformations during pregnancy, providing the possibility to consider termination of the pregnancy. As a result, in many cases the incidence of malformations at birth does not represent their true incidence.
To determine the impact of prenatal diagnosis and pregnancy termination on the relative incidence of malformations at birth among Jews and Muslim Arabs in Israel.
Data on selected major malformations in 2000-2003 were collected from the two large central databases of the Ministry of Health and the Central Bureau of Statistics which contain information regarding births, stillbirths and terminations of pregnancies.
For many malformations the total incidence was much higher than the incidence at birth. For almost all of the malformations studied, the total incidence was higher in Muslims than in Jews and the differences were further accentuated among the liveborn because of the differences in the rate of pregnancy terminations.
In order to detect possible influences of environmental or genetic factors on major malformations in Israel, it is critical to look at data including pregnancy terminations, stillbirths and live births.
对胎儿进行超声检查能够在孕期诊断出许多严重畸形，从而使终止妊娠成为可能。因此，在许多情况下，出生时畸形的发生率并不能代表其真实发生率。
确定产前诊断和终止妊娠对以色列犹太人和穆斯林阿拉伯人出生时畸形相对发生率的影响。
2000年至2003年选定的严重畸形数据，是从卫生部和中央统计局的两个大型中央数据库收集的，这些数据库包含有关出生、死产和终止妊娠的信息。
对于许多畸形来说，总发生率远高于出生时的发生率。对于几乎所有所研究的畸形，穆斯林中的总发生率高于犹太人，并且由于终止妊娠率的差异，活产儿中的差异进一步加剧。
为了检测环境或遗传因素对以色列严重畸形可能产生的影响，查看包括终止妊娠、死产和活产的数据至关重要。
