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使用多色光源时实现精确的放射变色光学计算机断层扫描成像。

Achieving accurate radiochromic optical-CT imaging when using a polychromatic light source.

作者信息

Thomas A, Pierquet M, Oldham M

机构信息

Dept of Radiation Oncology, Duke University Medical Center, Durham, NC, USA.

出版信息

J Phys Conf Ser. 2010;250(12045):210-214. doi: 10.1088/1742-6596/250/1/012045.

Abstract

Optical-CT performed with a broad spectrum light source can lead to inaccurate reconstructed attenuation coefficients (and hence dose) due to 'spectral warping' as the beam passes through the dosimeter. Some wavelengths will be attenuated more strongly than others depending on the absorption spectrum of the radiochromic dosimeter. A simulation was run to characterize the error introduced by the spectrum warping phenomena. Simulations of a typical dosimeter and delivered dose (6cm diameter, 2 Gy irradiation) showed reconstructed attenuation coefficients can be in error by >12% when compared to those obtained from a monochromatic scan. A method to correct for these errors is presented and preliminary data suggests that with the correction, polychromatic imaging can yield imaging results equal in accuracy to those of monochromatic imaging. The advantage is that polychromatic imaging may be less sensitive to prominent schlerring artefacts that are often observed in telecentric optical-CT scanning systems with tight bandwidth filters applied.

摘要

使用宽光谱光源进行光学CT时,由于光束穿过剂量计会产生“光谱畸变”,可能导致重建的衰减系数(以及剂量)不准确。根据放射变色剂量计的吸收光谱,某些波长的光比其他波长的光衰减得更强。进行了一项模拟,以表征光谱畸变现象引入的误差。对典型剂量计和传递剂量(直径6cm,2Gy照射)的模拟显示,与单色扫描获得的衰减系数相比,重建的衰减系数误差可能超过12%。提出了一种校正这些误差的方法,初步数据表明,通过校正,多色成像可以产生与单色成像精度相当的成像结果。其优点是,多色成像对在应用窄带宽滤波器的远心光学CT扫描系统中经常观察到的明显硬化伪影可能不太敏感。

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A method to correct for spectral artifacts in optical-CT dosimetry.一种校正光学 CT 剂量测定中光谱伪影的方法。
Phys Med Biol. 2011 Jun 7;56(11):3403-16. doi: 10.1088/0031-9155/56/11/014. Epub 2011 May 13.

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