Frank Wilhelm, Konta Brigitte
ARWIG (Arbeitskreis für wissenschaftliche Gesundheitsversorgung), Wien, Österreich.
GMS Health Technol Assess. 2005 Dec 21;1:Doc10.
The aim of the HTA report is to evaluate the effectiveness of cognitive training methods to treat cognitive disorders of dementia and other diseases with cognitive deficits. For this purpose, a systematic literature search was carried out first based on the DIMDI superbase retrieval. The identified publications were judged and selected by two independent, methodically competent experts. 33 publications were included in the report.Based on the studies for a normal cognitive development in old age a theory that healthy older people have a considerable capacity reserve for an improved performance in abstract abilities of thinking can be assumed. The first symptoms for older people at risk for dementia are a reduced cognitive capacity reserve. Cognitive training methods therefore focus abilities of abstract memory.APART FROM TYPES OF DEMENTIA ANOTHER TWO GROUPS OF DISEASES WITH COGNITIVE DEFICITS WERE INCLUDED IN THE HTA REPORT: cerebral lesions and schizophrenic psychoses.Studies with mild as well as forms of dementia heavy forms including the Alzheimer disease were included. The described training methods were very heterogeneous with regard to their contents, the temporal sequence and the outcome parameter. The studies were methodically partly contestable. Approximately a third of the studies of all publications could show improvements in the cognitive achievements by the training.Three studies concerning cognitive training methods in case of cerebral lesions were included. All three studies demonstrated a significant improvement in the training group in some outcome parameters.Special cognitive training methods were used for the treatment of cognitive deficits at schizophrenic psychoses. The neurocognitive training (NET), the "Cognitive Remediation Therapy" as well as the strategic training with coaching proved to be effective. The studies, however, were hardly comparable and very heterogeneous in detail.Summarising the cognitive training methods in case of severe dementia by reality orientation training (ROT) show selected success. In case of cerebral lesions in combination with schizophrenic psychoses successes could be proved in some parameters by applied cognitive training.Considering the heterogenity and the methodical deficiencies of the included studies it can be recommended, to carry out coordinated further studies with the goal to identify the success parameters of cognitive training methods and work out the relevant factors of effectiveness.
卫生技术评估报告的目的是评估认知训练方法治疗痴呆症及其他伴有认知缺陷疾病的认知障碍的有效性。为此,首先基于德国医学文献与信息研究所(DIMDI)超级数据库检索进行了系统的文献搜索。由两位独立的、方法学能力胜任的专家对检索到的出版物进行评判和筛选。33篇出版物被纳入该报告。基于对老年人正常认知发展的研究,可以假定一个理论,即健康的老年人在抽象思维能力提升方面有相当大的能力储备。痴呆症高危老年人的首个症状是认知能力储备下降。因此,认知训练方法聚焦于抽象记忆能力。除了痴呆症类型外,卫生技术评估报告还纳入了另外两组伴有认知缺陷的疾病:脑损伤和精神分裂症性精神病。研究涵盖了轻度痴呆形式以及重度痴呆形式,包括阿尔茨海默病。所描述的训练方法在内容、时间顺序和结果参数方面差异很大。这些研究在方法学上部分存在争议。所有出版物中约三分之一的研究表明训练可使认知成绩得到改善。纳入了三项关于脑损伤情况下认知训练方法的研究。所有三项研究均表明训练组在某些结果参数上有显著改善。针对精神分裂症性精神病的认知缺陷治疗使用了特殊的认知训练方法。神经认知训练(NET)、“认知康复疗法”以及带辅导的策略训练被证明是有效的。然而,这些研究之间几乎无法比较,且在细节上差异极大。通过现实导向训练(ROT)总结重度痴呆情况下的认知训练方法显示出一定成效。在脑损伤合并精神分裂症性精神病的情况下,应用认知训练在某些参数上证明是成功的。考虑到纳入研究的异质性和方法学缺陷,建议开展协调一致的进一步研究,目标是确定认知训练方法的成功参数并找出相关的有效性因素。