Pagni C A
2nd Chair of Neurosurgery, University of Torino, Italy.
Acta Neurochir Suppl (Wien). 1990;50:38-47. doi: 10.1007/978-3-7091-9104-0_8.
A detailed review, based on the literature and the author's own series, is given of the incidence of both early and late epilepsy following head injury related to age, severity and other specific features of the injury and clinical sequelae. Use of prophylactic anti-convulsant therapy, following head injury, remains controversial despite positive results of animal experiments. Hence, the author recommends that antiepileptic medication should be restricted to patients who have had at least two epileptic fits during the first two years after injury.
基于文献和作者自己的病例系列，对与年龄、损伤严重程度、损伤的其他具体特征以及临床后遗症相关的头部损伤后早期和晚期癫痫的发病率进行了详细综述。尽管动物实验取得了阳性结果，但头部损伤后预防性抗惊厥治疗的使用仍存在争议。因此，作者建议抗癫痫药物应仅限于在损伤后两年内至少发生两次癫痫发作的患者。
