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血清群WI的淋球菌感染中,衣原体合并感染是否更常见?

Is coexisting chlamydial infection more common in gonococcal infections with serogroup WI?

作者信息

McKenna J G, Young H, Moyes A, Smith I W

机构信息

Department of Medicine, Royal Infirmary of Edinburgh, UK.

出版信息

Int J STD AIDS. 1990 Sep;1(5):340-2. doi: 10.1177/095646249000100507.

DOI:10.1177/095646249000100507
PMID:2129109
Abstract

Over a 4-year period a total of 8974 women were screened for Neisseria gonorrhoeae and Chlamydia trachomatis. There were 489 cases of cervical gonorrhoea, 261 serogroup WI and 228 serogroup WII/III. A total of 169 (34.6%) cases had a dual infection with C. trachomatis, 92 from the WI serogroup and 77 from the WII/III. Using Fisher's exact test, no statistically significant difference was observed in the rates of chlamydial carriage between the two serogroups (P = 0.39). These findings are at odds with previously reported data, which suggested a biological interaction resulting in a positive correlation between colonization with serogroup WI and C. trachomatis. Possible reasons for the difference between the findings are discussed.

摘要

在4年的时间里,共有8974名女性接受了淋病奈瑟菌和沙眼衣原体的筛查。有489例宫颈淋病,其中261例为WI血清型,228例为WII/III血清型。共有169例(34.6%)病例同时感染了沙眼衣原体,其中92例来自WI血清型,77例来自WII/III血清型。使用Fisher精确检验,未观察到两个血清型之间沙眼衣原体携带率的统计学显著差异(P = 0.39)。这些发现与先前报道的数据不一致,先前的数据表明存在一种生物学相互作用,导致WI血清型定植与沙眼衣原体之间呈正相关。讨论了这些发现差异的可能原因。

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