Department of Adult Cardiac Surgery, G. Pasquinucci Heart Hospital, Monasterio Fondation-CNR, Via Aurelia Sud 54100, Massa, Italy.
Eur J Cardiothorac Surg. 2011 Aug;40(2):418-23. doi: 10.1016/j.ejcts.2010.12.012. Epub 2011 Feb 2.
To improve the long-term results of acute type A dissection repair, we developed a technique that combines radical surgical resection, and, at the same time, creates a safe and long landing zone for subsequent endovascular procedure on the descending aorta.
Since November 2006, 23 patients (62 ± 13 years) underwent aortic arch replacement concomitant with prophylactic debranching of the supra-aortic vessels, with a specially designed arch graft. The technique consists of replacing the ascending aorta and the aortic arch, and, at the same time, relocating the origin of the supra-aortic vessels just above the sinotubular junction creating a long and safe proximal landing zone for subsequent stent-graft deployment. Perfusion was antegrade through the ascending aorta during cooling and through the vascular prosthesis during rewarming. Distal arch anastomosis was performed under moderate hypothermic circulatory arrest for 25 ± 7 min and antegrade selective cerebral perfusion (46 ± 14 min). Cardiopulmonary bypass and aortic cross-clamp time were 138 ± 46 and 63 ± 22 min.
Hospital mortality was 4.3% (1/23). Postoperative morbidity includes five acute renal failures and four lung failures. No major neurological complications were observed. At follow-up (22±10 months), survival was 100% and two patients required an endovascular thoracic aorta repair for aneurysmal enlargement. In both cases, the stent grafts were successfully released in the landing zone created at the time of primary repair.
Our technique extends the suitability of endovascular therapies during type A acute dissection repair, creating a long and stable landing zone that allows safe performance of a second endovascular step if needed, both in the short- and long term.
为了提高急性A型夹层修复的长期效果,我们开发了一种技术,该技术结合了根治性手术切除,并同时为降主动脉后续的血管内治疗创造了一个安全且较长的着陆区。
自 2006 年 11 月以来,23 名患者(62±13 岁)接受了主动脉弓置换术,同时进行了主动脉弓上血管的预防性分支切除术,并使用了专门设计的弓部移植物。该技术包括替换升主动脉和主动脉弓,并同时将主动脉弓上血管的起源重新定位到窦管交界处上方,为后续支架移植的部署创造一个长而安全的近端着陆区。在冷却过程中通过升主动脉进行顺行灌注,在复温过程中通过血管移植物进行灌注。远端弓部吻合在中度低温循环停止下进行,时间为 25±7 分钟,顺行选择性脑灌注(46±14 分钟)。体外循环和主动脉阻断时间分别为 138±46 和 63±22 分钟。
住院死亡率为 4.3%(1/23)。术后并发症包括五例急性肾功能衰竭和四例肺部衰竭。无重大神经系统并发症。在随访(22±10 个月)时,生存率为 100%,两名患者因动脉瘤扩大需要进行血管内胸主动脉修复。在这两种情况下,支架移植物都成功地在初次修复时创建的着陆区释放。
我们的技术扩展了血管内治疗在急性 A 型夹层修复中的适用性,创建了一个长而稳定的着陆区,如果需要,无论是在短期还是长期,都可以安全地进行第二次血管内治疗。