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终末期治疗限制:对德国缓和医学学会医师成员实践的经验-伦理分析。

Limitation of treatment at the end of life: an empirical-ethical analysis regarding the practices of physician members of the German Society for Palliative Medicine.

机构信息

Institut für Medizinische Ethik und Geschichte der Medizin and History of Medicine, Ruhr-Universitaet Bochum, Malakowturm-Markstraße 258a, Bochum, Germany.

出版信息

J Med Ethics. 2011 Jun;37(6):327-32. doi: 10.1136/jme.2010.039248. Epub 2011 Feb 2.

Abstract

OBJECTIVES

To determine the frequencies and types of limitation of medical treatment performed by physician members of the German Society for Palliative Medicine and to analyse the findings with respect to clinical and ethical aspects of end-of-life practices.

DESIGN

Cross-sectional postal survey.

SETTING

Data collection via the secretary of the German Society for Palliative Medicine using the German language version of the EURELD survey instrument.

SUBJECTS

All 1645 physician members of the German Society for Palliative Medicine. Main outcome measures Types and frequencies of limitation of treatment and possible determinants.

RESULTS

901 physicians participated in the study (response rate 55.8%). Participants reported limitation of treatment in 69.1% of cases. These decisions most often affected artificial nutrition (19%), chemotherapy (14%), antibiotics (11%) and medication other than antibiotics (11%). In the majority of eligible cases, physicians estimated the life-shortening effect of limitation of treatment to be <7 days. However, estimations differ depending on the medical measures in question. Bivariate statistical analysis indicated that withholding of treatment was performed significantly more frequently for patients aged ≥65 years (p=0.019). In addition, there were significant associations between the incidence of limitation of treatment and the different diseases reported by respondents as the underlying cause of death.

CONCLUSION

The findings of this study provide information on the current state of an ethically and clinically challenging aspect of clinical practice and can serve as a starting point for further interdisciplinary research on normative and empirical aspects of treatment decision-making at the end of life.

摘要

目的

确定德国姑息治疗医师学会成员实施的治疗限制的频率和类型,并分析这些发现与临终实践的临床和伦理方面的关系。

设计

横断面邮寄调查。

设置

通过德国姑息治疗医师学会秘书使用 EURELD 调查工具的德语版本进行数据收集。

受试者

德国姑息治疗医师学会的所有 1645 名医师成员。主要观察指标:治疗限制的类型和频率以及可能的决定因素。

结果

901 名医师参与了这项研究(应答率为 55.8%)。参与者报告在 69.1%的情况下限制了治疗。这些决定最常影响人工营养(19%)、化疗(14%)、抗生素(11%)和除抗生素以外的药物(11%)。在大多数符合条件的情况下,医生估计限制治疗对缩短生命的影响<7 天。然而,估计值因所涉及的医疗措施而异。单变量统计分析表明,对年龄≥65 岁的患者更频繁地采取了治疗中止措施(p=0.019)。此外,治疗限制的发生率与受访者报告的不同疾病之间存在显著关联,这些疾病是导致死亡的根本原因。

结论

本研究的结果提供了关于临床实践中一个具有伦理和临床挑战性方面的现状信息,可以作为进一步研究临终治疗决策的规范性和实证方面的起点。

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