Costa L, Servodio Iammarrone C, Gigliotti S, Giuzio E, Buccafusca G
Instituto di Chirurgia dell'Apparato Locomotore e Chirurgia d'Urgenza, II Facoltà di Medicina e Chirurgia, Università degli Studi di Napoli.
Arch Putti Chir Organi Mov. 1990;38(1):177-86.
The authors, after referring the various pathogenetic hypotheses for Paget's disease (till the latest hypothesis of infection by slow-action virus) report their follow-up of forty-five patients with Paget's disease of bone; then explain their diagnostic method, and record complications stressing the sarcomatous degeneration. Finally they give details on their therapeutic treatment emphasizing the need of hematochemical and radiographic periodical controls in order to optimize the treatment case by case.
作者在提及佩吉特病的各种发病机制假说(直至最新的慢病毒感染假说)后,报告了他们对45例骨佩吉特病患者的随访情况;接着解释了他们的诊断方法,并记录了强调肉瘤样变性的并发症。最后,他们详细介绍了治疗方法,强调了血液化学和影像学定期检查的必要性,以便根据具体病例优化治疗方案。