Brandeis University, Waltham, MA 02454-9110, USA.
Am J Trop Med Hyg. 2011 Feb;84(2):200-7. doi: 10.4269/ajtmh.2011.10-0503.
The growing burden of dengue in endemic countries and outbreaks in previously unaffected countries stress the need to assess the economic impact of this disease. This paper synthesizes existing studies to calculate the economic burden of dengue illness in the Americas from a societal perspective. Major data sources include national case reporting data from 2000 to 2007, prospective cost of illness studies, and analyses quantifying underreporting in national routine surveillance systems. Dengue illness in the Americas was estimated to cost $2.1 billion per year on average (in 2010 US dollars), with a range of $1-4 billion in sensitivity analyses and substantial year to year variation. The results highlight the substantial economic burden from dengue in the Americas. The burden for dengue exceeds that from other viral illnesses, such as human papillomavirus (HPV) or rotavirus. Because this study does not include some components (e.g., vector control), it may still underestimate total economic consequences of dengue.
从社会角度来看，本文综合了现有的研究来计算美洲登革热疾病的经济负担。主要的数据来源包括 2000 年至 2007 年的国家病例报告数据、前瞻性疾病成本研究，以及量化国家常规监测系统中漏报情况的分析。美洲登革热疾病每年的平均估计费用为 21 亿美元（2010 年美元），在敏感性分析中范围在 10 亿至 40 亿美元之间，并且每年都有很大变化。结果突出了美洲登革热的巨大经济负担。登革热的负担超过了其他病毒疾病，如人乳头瘤病毒（HPV）或轮状病毒。由于本研究不包括某些组成部分（例如，病媒控制），因此它仍可能低估了登革热的总经济后果。
