Wenzel-Seifert K, Sharma A M, Keller F
Department of Internal Medicine, Universitätsklinikum Steglitz, Berlin, FRG.
Nephrol Dial Transplant. 1990;5(9):821-4. doi: 10.1093/ndt/5.9.821.
A 76-year-old woman with multiple allergic reactions was treated 17 times by haemodialysis. Symptoms of anaphylactoid reactions of increasing severity led to final death due to cardiorespiratory arrest. Anaphylactoid reactions appeared 5-30 min after the start of dialysis and lasted for 15-20 min. They first occurred on the 7th dialysis and consisted of hypotension, diarrhoea, bronchospasm, bradycardia and respiratory arrest. Change of dialysis regime, dialyser (gamma-sterilised, autoclaved), heparin, and administration of antihistamines, steroid, and adrenaline did not prevent these reactions.
一名76岁的女性有多种过敏反应，接受了17次血液透析治疗。类过敏反应症状日益严重，最终因心肺骤停死亡。类过敏反应在透析开始后5 - 30分钟出现，持续15 - 20分钟。首次发生在第7次透析时，表现为低血压、腹泻、支气管痉挛、心动过缓和呼吸骤停。改变透析方案、透析器（γ射线灭菌、高压灭菌）、肝素，以及使用抗组胺药、类固醇和肾上腺素均未能预防这些反应。
