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法国 18-74 岁人群中诊断和未诊断糖尿病的首次全国流行率估计:2006/2007 年法国营养与健康调查。

A first national prevalence estimate of diagnosed and undiagnosed diabetes in France in 18- to 74-year-old individuals: the French Nutrition and Health Survey 2006/2007.

机构信息

Department of Chronic Diseases and Injuries, French Institute for Public Health Surveillance, Saint Maurice, France.

出版信息

Diabet Med. 2011 May;28(5):583-9. doi: 10.1111/j.1464-5491.2011.03250.x.

Abstract

AIMS

To estimate the nationwide prevalence of diagnosed and undiagnosed diabetes and pre-diabetes in adults residing in France.

METHODS

A probability sample of a non-institutionalized civilian population residing throughout the whole of continental France was recruited from February 2006 to March 2007 for the French Nutrition and Health Survey. All individuals aged between 18 and 74 years who agreed to participate in the survey were included; thus there were 3115 participants, 2102 of whom were undergoing biochemical assessments. The prevalence of diagnosed diabetes was estimated using self-reported diabetes history and the prevalence of undiagnosed diabetes was estimated using fasting plasma glucose ≥ 7.0 mmol/l or HbA(1c) ≥ 6.5% (≥ 48 mmol/mol).

RESULTS

The prevalence of diagnosed diabetes was 4.6%, 95% CI 3.6-5.7. The prevalence of undiagnosed diabetes according to standard fasting plasma glucose criteria was 1% (95% CI 0.6-1.7) and contributed to less than 20% of all cases of diabetes. This proportion decreased with age from 30% in 30- to 54-year-olds to 12% in 55- to 74-year-olds. Based on HbA(1c) criteria, the prevalence of undiagnosed diabetes was 0.8% (95% CI 0.4-1.6).

CONCLUSIONS

The prevalence of diagnosed diabetes in adults in France is comparable with recent estimates from Northern Europe. The percentage of total diabetes that is undiagnosed is low in France, which may be explained by a widely practised strategy of opportunist screening. During the past years, improvements in diabetes care and increased awareness may have contributed towards decreasing the prevalence of undiagnosed diabetes more widely in Europe, and studies should further monitor such improvements.

摘要

目的

估计法国成年人中已确诊和未确诊的糖尿病和糖尿病前期的全国患病率。

方法

2006 年 2 月至 2007 年 3 月,采用概率抽样方法,从法国大陆各地招募了一个非住院的平民样本,进行法国营养与健康调查。所有年龄在 18 至 74 岁之间、同意参与调查的人都包括在内;因此,共有 3115 名参与者,其中 2102 名进行了生化评估。通过自我报告的糖尿病病史来估计已确诊糖尿病的患病率,通过空腹血糖≥7.0mmol/l 或 HbA(1c)≥6.5%(≥48mmol/mol)来估计未确诊糖尿病的患病率。

结果

已确诊糖尿病的患病率为 4.6%,95%可信区间为 3.6-5.7。根据标准空腹血糖标准,未确诊糖尿病的患病率为 1%(95%可信区间为 0.6-1.7),不到所有糖尿病病例的 20%。这一比例随年龄增长而降低,从 30-54 岁人群的 30%降至 55-74 岁人群的 12%。根据 HbA(1c)标准,未确诊糖尿病的患病率为 0.8%(95%可信区间为 0.4-1.6)。

结论

法国成年人中已确诊糖尿病的患病率与北欧最近的估计值相当。法国未确诊糖尿病的比例较低,这可能是由于广泛实施了机会性筛查策略。在过去几年中,欧洲各地改善了糖尿病治疗和提高了认识,这可能有助于更广泛地降低未确诊糖尿病的患病率,研究应进一步监测这些改善。

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