The Research Unit for General Practice and Section of General Practice, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.
BMC Public Health. 2011 Feb 4;11:80. doi: 10.1186/1471-2458-11-80.
Many diabetic patients fear visual loss as the worst consequence of diabetes. In most studies the main eye pathology is assigned as the cause of visual impairment. This study analysed a broad range of possible ocular and non-ocular predictors of visual impairment prospectively in patients newly diagnosed with clinical type 2 diabetes.
Data were from a population-based cohort of 1,241 persons newly diagnosed with clinical, often symptomatic type 2 diabetes aged ≥ 40 years. After 6 years, 807 patients were followed up. Standard eye examinations were done by practising ophthalmologists.
At diabetes diagnosis median age was 65.5 years. Over 6 years, the prevalence of blindness (visual acuity of best seeing eye ≤ 0.1) rose from 0.9% (11/1,241) to 2.4% (19/807) and the prevalence of moderate visual impairment (> 0.1; < 0.5) rose from 5.4% (67/1,241) to 6.7% (54/807). The incidence (95% confidence interval) of blindness was 40.2 (25.3-63.8) per 10,000 patient-years. Baseline predictors of level of visual acuity (age, age-related macular degeneration (AMD), cataract, living alone, low self-rated health, and sedentary life-style) and speed of continued visual loss (age, AMD, diabetic retinopathy (DR), cataract, living alone, and high fasting triglycerides) were identified.
In a comprehensive assessment of predictors of visual impairment, even in a health care system allowing self-referral to free eye examinations, treatable eye pathologies such as DR and cataract emerge together with age as the most notable predictors of continued visual loss after diabetes diagnosis. Our results underline the importance of eliminating barriers to efficient eye care by increasing patients' and primary care practitioners' awareness of the necessity of regular eye examinations and timely surgical treatment.
许多糖尿病患者担心视力丧失是糖尿病最严重的后果。在大多数研究中,主要的眼部病变被认为是导致视力障碍的原因。本研究前瞻性分析了新诊断为临床 2 型糖尿病患者中广泛的眼部和非眼部预测因素。
数据来自于一项基于人群的队列研究,共纳入 1241 名年龄≥40 岁、新诊断为临床、常伴有症状的 2 型糖尿病患者。6 年后,对 807 名患者进行了随访。由执业眼科医生进行标准眼部检查。
糖尿病诊断时的中位年龄为 65.5 岁。6 年内,失明(最佳视力眼视力≤0.1)的患病率从 0.9%(11/1241)上升至 2.4%(19/807),中度视力障碍(>0.1;<0.5)的患病率从 5.4%(67/1241)上升至 6.7%(54/807)。失明的发病率(95%置信区间)为 40.2(25.3-63.8)/10000 患者年。视力水平(年龄、年龄相关性黄斑变性(AMD)、白内障、独居、自我健康评价低和久坐生活方式)和视力持续下降速度(年龄、AMD、糖尿病视网膜病变(DR)、白内障、独居和空腹甘油三酯高)的基线预测因素已确定。
在对视力障碍预测因素的综合评估中,即使在允许患者自行转诊接受免费眼部检查的医疗保健体系中,DR 和白内障等可治疗的眼部病变以及年龄仍然是糖尿病诊断后视力持续下降的最显著预测因素。我们的研究结果强调了通过提高患者和初级保健医生对定期眼部检查和及时手术治疗的必要性的认识,消除有效眼部护理障碍的重要性。