Clark James H, Aggarwal Pooja, Wang Nae-Yuh, Robinson Raymond, Niparko John K, Lin Frank R
Department of Otolaryngology-Head & Neck Surgery, Johns Hopkins School of Medicine, Baltimore, MD 21287, USA.
Int J Pediatr Otorhinolaryngol. 2011 Apr;75(4):549-53. doi: 10.1016/j.ijporl.2011.01.015. Epub 2011 Feb 5.
To develop preliminary "growth curves" of Functioning after Pediatric Cochlear Implantation (FAPCI) scores using a cross-sectional sample of normal hearing children and to compare these curves to trajectories of FAPCI scores in children receiving cochlear implants.
Quantile regression was used to develop growth curves from the FAPCI scores of a cross-sectional sample of 82 normal hearing children (age range 7 months-5 years). Trajectories of FAPCI scores from a longitudinal cohort of 75 children with cochlear implants (age range 1-5 years) were compared to these growth curves.
FAPCI scores were positively associated with increasing age in normal hearing children with a rapid increase in scores observed at earlier ages followed by a plateau at age 3 years. FAPCI trajectories for cochlear-implanted children varied with age at implantation and did not reach a plateau until age 5-6 years.
Normal hearing children demonstrated increasing FAPCI scores with age, and these preliminary growth curves allow for the interpretation of a cochlear-implanted child's FAPCI scores in comparison to normal hearing children. Additional research using a larger, longitudinal cohort of normal hearing children will be needed to develop definitive normative FAPCI trajectories.
利用正常听力儿童的横断面样本制定小儿人工耳蜗植入后功能(FAPCI)评分的初步“生长曲线”,并将这些曲线与接受人工耳蜗植入儿童的FAPCI评分轨迹进行比较。
采用分位数回归方法,根据82名正常听力儿童(年龄范围7个月至5岁)的横断面样本的FAPCI评分制定生长曲线。将75名人工耳蜗植入儿童(年龄范围1至5岁)纵向队列的FAPCI评分轨迹与这些生长曲线进行比较。
在正常听力儿童中,FAPCI评分与年龄增长呈正相关,在早期年龄观察到评分快速增加,随后在3岁时趋于平稳。人工耳蜗植入儿童的FAPCI轨迹随植入年龄而变化,直到5至6岁才趋于平稳。
正常听力儿童的FAPCI评分随年龄增加,这些初步生长曲线有助于将人工耳蜗植入儿童的FAPCI评分与正常听力儿童进行比较。需要使用更大规模的正常听力儿童纵向队列进行进一步研究,以制定明确的FAPCI评分标准轨迹。