Srivastava E D, Swift G L, Wilkinson S, Williams G T, Evans B K, Rhodes J
University Hospital of Wales, Heath Park, Cardiff.
Aliment Pharmacol Ther. 1990 Dec;4(6):577-81. doi: 10.1111/j.1365-2036.1990.tb00505.x.
Eleven patients with active proctitis or proctosigmoiditis completed one month's treatment with tripotassium dicitrato bismuthate enemas administered at night. Symptoms, sigmoidoscopic appearances, and the histological grade of acute inflammation were assessed at the commencement of therapy and after one month. An overall score of these features showed improvement in 9 of 11 patients, which encourages further investigation of bismuth in controlled trials for patients with inflammatory bowel disease.
11例活动性直肠炎或直肠乙状结肠炎患者接受了为期1个月的夜间用枸橼酸铋钾灌肠治疗。在治疗开始时和1个月后评估症状、乙状结肠镜检查表现以及急性炎症的组织学分级。这些特征的综合评分显示，11例患者中有9例病情有所改善，这鼓励在炎症性肠病患者的对照试验中对铋进行进一步研究。
