Department of Pathobiology and Quality Control, Artemia and Aquatic Animals Research Institute, Urmia University, Iran.
Fish Shellfish Immunol. 2011 Mar;30(3):923-8. doi: 10.1016/j.fsi.2011.01.016. Epub 2011 Feb 3.
The effects of dietary whole cell yeast (Saccharomyces cerevisiae), n-3 HUFA-enriched yeast and treated yeast cells with beta-mercapto-ethanol (2ME) on immunity, growth performance and disease resistance to Yersinia ruckeri were investigated in Oncorhynchus mykiss. During 30 days, juvenile rainbow trout were fed diets supplemented with different forms of yeast at 5 × 10(7) CFU g(-1) or a control diet. After the feeding trial, remaining fish of each treatment were challenged by pathogenic Yersinia ruckeri and kept under observation for 14 days to record clinical signs and daily mortality rate. Yeast supplementation in all treatment groups significantly promoted the growth performance compared to control group. A significantly increase was also observed in immune responses in juvenile fish fed 2ME-treated yeast diet. More ever, the lowest fish mortality was obtained in this treatment group. The present results show that a diet supplemented with 2ME-treated yeast stimulates the immune system and growth of juvenile rainbow trout thus enhancing their resistance against Y. ruckeri.
在虹鳟中研究了日粮全细胞酵母（酿酒酵母）、富含 n-3 HUFA 的酵母和用β-巯基乙醇（2ME）处理的酵母细胞对免疫、生长性能和对鲁氏耶尔森氏菌（Yersinia ruckeri）的抵抗力的影响。在 30 天的时间里，用不同形式的酵母补充剂喂养幼龄虹鳟鱼，添加剂量为 5×10(7)CFU g(-1)或对照饮食。在喂养试验结束后，用致病性鲁氏耶尔森氏菌对每个处理组的剩余鱼类进行攻毒，并观察 14 天以记录临床症状和每日死亡率。与对照组相比，所有处理组的酵母补充剂都显著促进了生长性能。还观察到，用 2ME 处理的酵母饲料喂养的幼鱼的免疫反应也显著增加。此外，在该处理组中获得了最低的鱼类死亡率。本研究结果表明，日粮中添加 2ME 处理的酵母可刺激幼龄虹鳟的免疫系统和生长，从而增强其对 Y.ruckeri 的抵抗力。
