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单中心研究比较标准的顶端解剖与改良技术,以促进腹腔镜根治性前列腺切除术中的膀胱-尿道吻合。

Single-centre study comparing standard apical dissection with a modified technique to facilitate vesico-urethral anastomosis during laparoscopic radical prostatectomy.

机构信息

Department of Urology, the Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou 510630, China.

出版信息

Asian J Androl. 2011 May;13(3):494-8. doi: 10.1038/aja.2010.110. Epub 2011 Feb 7.

Abstract

A modified apical dissection of the prostate to improve the efficiency of vesico-urethral anastomosis (VUA) in laparoscopic radical prostatectomy (LRP) was reported. A total of 42 patients were randomly selected and enrolled in this study. A standard LRP was performed in 21 patients (group 1), whereas a novel, modified apical dissection of the prostate in LRP was performed in another 21 patients (group 2). Surgical data, total operative time, VUA time, extravasation rate, catheterisation time, occurrence of anastomotic strictures, and the early and late continence rates were analysed statistically. No differences in clinical or pathological characteristics were determined between the two groups. The total operative time, VUA time, blood loss and catheterisation time were lower in group 2, which received the novel, modified technique compared with group 1, which received the standard technique to dissect the apex of the prostate (P < 0.01 for each variable). Regarding the extravasation rate and the occurrence of anastomotic strictures, no significant differences were found between the two groups (P > 0.05 for each). After catheter removal, a statistically significant difference in the continence rates was present at 3 and 30 days post operation in the two groups (P < 0.01, respectively). At 90 days post operation, the difference, although still present, was no longer statistically significant (P > 0.05). The novel, modified apical dissection of the prostate facilitates the VUA and significantly improves the efficacy of the procedure and early restoration of continence.

摘要

一种改良的前列腺尖部解剖方法被报道可以提高腹腔镜前列腺根治性切除术(LRP)中膀胱尿道吻合术(VUA)的效率。共有 42 名患者被随机选择并纳入本研究。21 名患者接受标准 LRP(组 1),而另外 21 名患者接受改良的前列腺尖部解剖的新型 LRP(组 2)。对手术数据、总手术时间、VUA 时间、漏尿率、导尿时间、吻合口狭窄发生率以及早期和晚期尿控率进行了统计学分析。两组患者在临床和病理特征方面无差异。与接受标准前列腺尖部解剖的组 1 相比,接受新型改良前列腺尖部解剖的组 2 的总手术时间、VUA 时间、出血量和导尿时间均较低(各变量 P<0.01)。关于漏尿率和吻合口狭窄发生率,两组间无显著差异(各变量 P>0.05)。导尿管拔除后,两组患者在术后 3 天和 30 天的尿控率存在显著差异(分别为 P<0.01)。术后 90 天,虽然差异仍然存在,但不再具有统计学意义(P>0.05)。改良的前列腺尖部解剖方法有助于 VUA,并显著提高手术的疗效和早期恢复尿控。

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