Pulsrikarn Chaiwat, Bangtrakulnonth Aroon, Pornruangwong Srirat, Sriyapai Thayat, Sawanpanyalert Pathom, Aswapokee Nalinee, Techasathit Wichai
WHO National Salmonella and Shigella Center, National Institute of Health, Department of Medical Sciences, Ministry of Public Health, Nonthaburi, Thailand.
J Med Assoc Thai. 2009 Aug;92 Suppl 4:S76-81.
To study the species and the serotypes of the clinical isolates of Shigella obtained from patients in Thailand.
The World Health Organization National Salmonella and Shigella Center Thailand, had confirmed the species and performed serotype identification of 1,913 clinical isolates of Shigella collected from the laboratory network of Department of Medical Sciences and the collaborated hospitals across Thailand from 2001 to 2005.
Between the year 2001 and 2005, 728, 481, 160, 247, 297 clinical isolates were tested, respectively. There were 5 isolates of S. dysenteriae (group A), 416 isolates of S. flexneri (group B), 4 isolates of S. boydii (group C) and 1,488 isolates of S. sonnei (group D). A total of 21 Shigella serotypes were identified and there were 3 serotypes in group A, 11 serotypes in group B, 4 serotypes in group C, and 3 serotypes in group D. Throughout these five years, the five common serotypes were S. sonnei Phases I and II, 28.6% (548 isolates); S. sonnei Phase I, 24.6% (470 isolates); S. sonnei Phase II, 24.6% (470 isolates); S. flexneri Type 2a, 10.9% (208 isolates), and S. flexneri Type 3a, 6.3% (121 isolates), respectively.
At the national scale in Thailand from 2001 to 2005, S. sonnei was the most frequent Shigella spp. isolated from patients in Thailand. In addition, S. dysenteriae and S. boydii were extremely uncommon. These findings are important in future vaccine development.
研究从泰国患者中分离出的志贺氏菌临床分离株的种类和血清型。
世界卫生组织泰国国家沙门氏菌和志贺氏菌中心对2001年至2005年从泰国医学科学部实验室网络及合作医院收集的1913株志贺氏菌临床分离株进行了种类确认和血清型鉴定。
2001年至2005年期间，分别检测了728、481、160、247、297株临床分离株。其中有5株痢疾志贺氏菌（A组）、416株福氏志贺氏菌（B组）、4株鲍氏志贺氏菌（C组）和1488株宋内志贺氏菌（D组）。共鉴定出21种志贺氏菌血清型，其中A组3种血清型，B组11种血清型，C组4种血清型，D组3种血清型。在这五年中，五种常见血清型分别为宋内志贺氏菌I相和II相，占28.6%（548株）；宋内志贺氏菌I相，占24.6%（470株）；宋内志贺氏菌II相，占24.6%（470株）；福氏志贺氏菌2a型，占10.9%（208株），福氏志贺氏菌3a型，占6.3%（121株）。
在2001年至2005年泰国全国范围内，宋内志贺氏菌是从泰国患者中分离出的最常见的志贺氏菌属。此外，痢疾志贺氏菌和鲍氏志贺氏菌极为罕见。这些发现对未来疫苗开发具有重要意义。
