Department of Chemistry and Biochemistry and Thermal Biology Institute, Montana State University, Bozeman, MT 59717, USA.
Structure. 2011 Feb 9;19(2):142-4. doi: 10.1016/j.str.2011.01.003.
In this issue, Wang et al. (2011) show that the CRISPR endonuclease Cas6 wraps an unstructured CRISPR RNA repeat around its surface to achieve recognition and cleavage, suggesting that palindromic RNA is not a feature of many CRISPR subtypes.
在本期中,Wang 等人(2011 年)表明,CRISPR 内切酶 Cas6 环绕其表面包裹未折叠的 CRISPR RNA 重复序列以实现识别和切割,这表明发夹状 RNA 不是许多 CRISPR 亚型的特征。