Moraillon A, Moraillon R
Ann Rech Vet. 1978;9(1):43-54.
An original microplate seroneutralization technique was developed in order to study the existence of antibodies against equine viral arteritis. The technique involves a high amount of complement, and has allowed to demonstrate antibodies in 18.5% out of 4,037 horses examined. Titers varied not or little during periods as long as 6 years. Among 3,324 sera samples from French horses, a 15.2% frequency of antibodies was shown. The infection level was not very different between breeds, which is different from results obtained in the U.S.A. with another technique. The infection level increased regularly from 1 to 20 years of age, but, for a constant age, the percentage decreased with the year of birth, between 1950 and 1970. Eight individual infection cases have been identified between 1966 and 1974. It seems that more often the disease occurs without clinical symptoms, or sometimes manifests itself through sporadic abortion. Serological marks of infection have been found at variable levels in all the countries of Europe and Africa investigated. In Africa, a higher level (37.1% among 468 sera) was observed.
为研究抗马病毒性动脉炎抗体的存在情况，开发了一种原始的微孔板血清中和技术。该技术需要大量补体，在4037匹受检马匹中，有18.5%检测出抗体。在长达6年的时间里，抗体滴度变化不大或没有变化。在3324份法国马匹的血清样本中，抗体出现频率为15.2%。不同品种之间的感染水平差异不大，这与美国用另一种技术得到的结果不同。感染水平从1岁到20岁呈规律性上升，但对于相同年龄的马匹，在1950年至1970年期间，感染百分比随出生年份下降。1966年至1974年期间，已确认8例个体感染病例。似乎该病更多时候无临床症状，或有时表现为散发性流产。在欧洲和非洲所有被调查的国家，均发现了不同水平的感染血清学标志物。在非洲，观察到较高水平（468份血清中为37.1%）。
