鼠类免疫球蛋白同种异型（同种型）：V. IgM 同种异型的特征。
Immunoglobulin isoantigens (allotypes) in the mouse : V. Characterization of IgM allotypes.
机构信息
Department of Genetics, Stanford University School of Medicine, 94305, Stanford, California.
出版信息
Immunogenetics. 1978 Dec;7(1):213-30. doi: 10.1007/BF01844009.
Murine antisera raised against allogeneic lymphoid cells often contain antibodies to IgM allotypes. Rarely, allotypic antibodies to IgM have been found after immunization withB. pertussis anti-B. pertussis conjugates. Using both types of antibodies, we have defined a new constant-region locus for both secreted and membrane-bound μ chains. This locus,Ig-6, is closely linked to the previously described H-chain constant-region loci (Ig-1 throughIg-5) and is subject to allelic exclusion. We have identified three alleles and four antigenic specificities ofIg-6.
鼠抗同种异体淋巴细胞血清常含有针对 IgM 同种异型的抗体。在接种 B. pertussis 抗 B. pertussis 结合物后，很少发现针对 IgM 的同种异型抗体。使用这两种类型的抗体，我们已经确定了一个新的分泌型和膜结合型 μ 链恒定区基因座，即 Ig-6。该基因座与先前描述的 H 链恒定区基因座（Ig-1 至 Ig-5）紧密连锁，并受等位基因排斥的控制。我们已经鉴定出 Ig-6 的三个等位基因和四个抗原特异性。
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