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肝素杆菌模式菌株(HIM 762-3)的全基因组序列

Complete genome sequence of Pedobacter heparinus type strain (HIM 762-3).

作者信息

Han Cliff, Spring Stefan, Lapidus Alla, Del Rio Tijana Glavina, Tice Hope, Copeland Alex, Cheng Jan-Fang, Lucas Susan, Chen Feng, Nolan Matt, Bruce David, Goodwin Lynne, Pitluck Sam, Ivanova Natalia, Mavromatis Konstantinos, Mikhailova Natalia, Pati Amrita, Chen Amy, Palaniappan Krishna, Land Miriam, Hauser Loren, Chang Yun-Juan, Jeffries Cynthia C, Saunders Elizabeth, Chertkov Olga, Brettin Thomas, Göker Markus, Rohde Manfred, Bristow Jim, Eisen Jonathan A, Markowitz Victor, Hugenholtz Philip, Kyrpides Nikos C, Klenk Hans-Peter, Detter John C

出版信息

Stand Genomic Sci. 2009 Jul 20;1(1):54-62. doi: 10.4056/sigs.22138.

Abstract

Pedobacter heparinus (Payza and Korn 1956) Steyn et al. 1998 comb. nov. is the type species of the rapidly growing genus Pedobacter within the family Sphingobacteriaceae of the phylum 'Bacteroidetes'. P. heparinus is of interest, because it was the first isolated strain shown to grow with heparin as sole carbon and nitrogen source and because it produces several enzymes involved in the degradation of mucopolysaccharides. All available data about this species are based on a sole strain that was isolated from dry soil. Here we describe the features of this organism, together with the complete genome sequence, and annotation. This is the first report on a complete genome sequence of a member of the genus Pedobacter, and the 5,167,383 bp long single replicon genome with its 4287 protein-coding and 54 RNA genes is part of the Genomic Encyclopedia of Bacteria and Archaea project.

摘要

肝素节杆菌(Payza和Korn,1956年)Steyn等人,1998年组合新名,是“拟杆菌门”鞘脂杆菌科中快速生长的节杆菌属的模式种。肝素节杆菌备受关注,因为它是首个被分离出的、能以肝素作为唯一碳源和氮源生长的菌株,还因为它能产生多种参与黏多糖降解的酶。关于该物种的所有现有数据均基于从干燥土壤中分离出的单一菌株。在此,我们描述了该生物体的特征,以及完整的基因组序列和注释。这是关于节杆菌属成员完整基因组序列的首篇报道,这个长度为5,167,383 bp的单复制子基因组及其4287个蛋白质编码基因和54个RNA基因,是细菌和古菌基因组百科全书项目的一部分。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/23c3/3035210/0b05bf67f39a/sigs.22138-f1.jpg

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