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基因组序列最小信息(MIGS)规范

The minimum information about a genome sequence (MIGS) specification.

作者信息

Field Dawn, Garrity George, Gray Tanya, Morrison Norman, Selengut Jeremy, Sterk Peter, Tatusova Tatiana, Thomson Nicholas, Allen Michael J, Angiuoli Samuel V, Ashburner Michael, Axelrod Nelson, Baldauf Sandra, Ballard Stuart, Boore Jeffrey, Cochrane Guy, Cole James, Dawyndt Peter, De Vos Paul, DePamphilis Claude, Edwards Robert, Faruque Nadeem, Feldman Robert, Gilbert Jack, Gilna Paul, Glöckner Frank Oliver, Goldstein Philip, Guralnick Robert, Haft Dan, Hancock David, Hermjakob Henning, Hertz-Fowler Christiane, Hugenholtz Phil, Joint Ian, Kagan Leonid, Kane Matthew, Kennedy Jessie, Kowalchuk George, Kottmann Renzo, Kolker Eugene, Kravitz Saul, Kyrpides Nikos, Leebens-Mack Jim, Lewis Suzanna E, Li Kelvin, Lister Allyson L, Lord Phillip, Maltsev Natalia, Markowitz Victor, Martiny Jennifer, Methe Barbara, Mizrachi Ilene, Moxon Richard, Nelson Karen, Parkhill Julian, Proctor Lita, White Owen, Sansone Susanna-Assunta, Spiers Andrew, Stevens Robert, Swift Paul, Taylor Chris, Tateno Yoshio, Tett Adrian, Turner Sarah, Ussery David, Vaughan Bob, Ward Naomi, Whetzel Trish, San Gil Ingio, Wilson Gareth, Wipat Anil

机构信息

Natural Environmental Research Council Centre for Ecology and Hydrology, Oxford OX1 3SR, UK.

出版信息

Nat Biotechnol. 2008 May;26(5):541-7. doi: 10.1038/nbt1360.

Abstract

With the quantity of genomic data increasing at an exponential rate, it is imperative that these data be captured electronically, in a standard format. Standardization activities must proceed within the auspices of open-access and international working bodies. To tackle the issues surrounding the development of better descriptions of genomic investigations, we have formed the Genomic Standards Consortium (GSC). Here, we introduce the minimum information about a genome sequence (MIGS) specification with the intent of promoting participation in its development and discussing the resources that will be required to develop improved mechanisms of metadata capture and exchange. As part of its wider goals, the GSC also supports improving the 'transparency' of the information contained in existing genomic databases.

摘要

随着基因组数据量呈指数级增长,以标准格式进行电子捕获这些数据势在必行。标准化活动必须在开放获取和国际工作机构的支持下进行。为了解决围绕更好地描述基因组研究而产生的问题,我们成立了基因组标准联盟(GSC)。在此,我们介绍关于基因组序列的最小信息(MIGS)规范,旨在促进参与其开发,并讨论开发改进的元数据捕获和交换机制所需的资源。作为其更广泛目标的一部分,GSC还支持提高现有基因组数据库中所含信息的“透明度”。

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