Sims David, Brettin Thomas, Detter John C, Han Cliff, Lapidus Alla, Copeland Alex, Glavina Del Rio Tijana, Nolan Matt, Chen Feng, Lucas Susan, Tice Hope, Cheng Jan-Fang, Bruce David, Goodwin Lynne, Pitluck Sam, Ovchinnikova Galina, Pati Amrita, Ivanova Natalia, Mavrommatis Konstantinos, Chen Amy, Palaniappan Krishna, D'haeseleer Patrik, Chain Patrick, Bristow Jim, Eisen Jonathan A, Markowitz Victor, Hugenholtz Philip, Schneider Susanne, Göker Markus, Pukall Rüdiger, Kyrpides Nikos C, Klenk Hans-Peter
Stand Genomic Sci. 2009 Jul 20;1(1):12-20. doi: 10.4056/sigs.761.
Kytococcus sedentarius (ZoBell and Upham 1944) Stackebrandt et al. 1995 is the type strain of the species, and is of phylogenetic interest because of its location in the Dermacoccaceae, a poorly studied family within the actinobacterial suborder Micrococcineae. Kytococcus sedentarius is known for the production of oligoketide antibiotics as well as for its role as an opportunistic pathogen causing valve endocarditis, hemorrhagic pneumonia, and pitted keratolysis. It is strictly aerobic and can only grow when several amino acids are provided in the medium. The strain described in this report is a free-living, nonmotile, Gram-positive bacterium, originally isolated from a marine environment. Here we describe the features of this organism, together with the complete genome sequence, and annotation. This is the first complete genome sequence of a member of the family Dermacoccaceae and the 2,785,024 bp long single replicon genome with its 2639 protein-coding and 64 RNA genes is part of the Genomic Encyclopedia of Bacteria and Archaea project.
定居库克菌(佐贝尔和厄普姆,1944年)斯塔克布兰特等人,1995年,是该物种的模式菌株,因其在皮球菌科中的位置而具有系统发育学研究价值,皮球菌科是放线菌亚目微球菌科内一个研究较少的科。定居库克菌以产生寡酮类抗生素以及作为引起瓣膜性心内膜炎、出血性肺炎和凹坑状角质松解症的机会致病菌而闻名。它是严格需氧菌,只有在培养基中提供几种氨基酸时才能生长。本报告中描述的菌株是一种自由生活、无运动性的革兰氏阳性细菌,最初从海洋环境中分离出来。在此,我们描述了该生物体的特征,以及完整的基因组序列和注释。这是皮球菌科成员的首个完整基因组序列,这个2785024 bp长的单复制子基因组及其2639个蛋白质编码基因和64个RNA基因是细菌和古菌基因组百科全书项目的一部分。