用锝-99m甲氧基异丁基异腈评估心肌灌注和存活情况。
Assessment of myocardial perfusion and viability with technetium-99m methoxyisobutyl isonitrile.
作者信息
Beller G A, Sinusas A J, Watson D D
机构信息
Department of Medicine, University of Virginia Health Sciences Center, Charlottesville 22908.
出版信息
Trans Am Clin Climatol Assoc. 1991;102:41-51.
Abstract
The clinical application of Tc-99m Sestamibi imaging in acute myocardial infarction should be most useful. The capability of assessing risk area during acute coronary occlusion and degree of myocardial salvage after reperfusion offers a noninvasive means to assess the benefit of therapeutic interventions aimed at reducing myocardial ischemic injury. Further studies in larger numbers of patients appear warranted to identify the precise worth of this new imaging technique relative to other existing noninvasive imaging methodologies in clinical practice.
摘要
锝-99m 甲氧基异丁基异腈显像在急性心肌梗死中的临床应用应该是最有用的。评估急性冠状动脉闭塞期间的危险区域以及再灌注后心肌挽救程度的能力，为评估旨在减少心肌缺血损伤的治疗干预措施的益处提供了一种非侵入性手段。有必要对更多患者进行进一步研究，以确定这种新的成像技术相对于临床实践中其他现有的非侵入性成像方法的确切价值。
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本文引用的文献
1
Coronary artery reperfusion in acute myocardial infarction: beneficial effects of intracoronary streptokinase on left ventricular salvage and performance.
Am Heart J. 1981 Dec;102(6 Pt 2):1168-77. doi: 10.1016/0002-8703(81)90648-7.
2
Coronary artery reperfusion in acute myocardial infarction: assessment by pre- and postintervention thallium-201 myocardial perfusion imaging.
Am J Cardiol. 1985 Apr 1;55(8):889-95. doi: 10.1016/0002-9149(85)90712-x.
3
Myocardial kinetics of technetium-99m-hexakis-2-methoxy-2-methylpropyl-isonitrile.锝-99m-六甲基异腈的心肌动力学
Circulation. 1988 Feb;77(2):491-8. doi: 10.1161/01.cir.77.2.491.
4
Effect of ischemia and postischemic dysfunction on myocardial uptake of technetium-99m-labeled methoxyisobutyl isonitrile and thallium-201.缺血及缺血后功能障碍对心肌摄取锝-99m标记的甲氧基异丁基异腈和铊-201的影响。
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