Georgia Health Sciences University, Children's Medical Center, Department of Radiology, 1120 15th Avenue, Augusta, GA 30912, United States.
Eur J Radiol. 2011 Dec;80(3):e446-50. doi: 10.1016/j.ejrad.2011.01.010. Epub 2011 Feb 8.
The purpose of the study is to determine whether there are cross-sectional imaging features of pediatric rhabdomyosarcoma that are specific to the different pathologic subtypes of the tumor.
Medical records of 14 pediatric patients who were diagnosed with rhabdomyosarcoma were reviewed retrospectively. Patient demographics, including age and sex, as well as final pathologic report were obtained. The initial CT, MRI, or both obtained at presentation, prior to the diagnosis being established, were reviewed by two radiologists. We recorded tumor features including site, size, margins, local extension, and presence of metastases. Presence of calcification, hemorrhage, or necrosis as well as attenuation and heterogeneity of the tumor were also recorded.
Ten of our fourteen patients were formally diagnosed with the embryonal subtype of rhabdomyosarcoma, while three were found to have the alveolar subtype, and one subtype was poorly differentiated. There was no significant difference in the attenuation and in the heterogeneity of the tumor between the embryonal and the alveolar subtype on CT.
Imaging features at presentation, such as attenuation and heterogeneity, could not correlate to the pathologic subtype of pediatric rhabdomyosarcoma.
本研究旨在确定小儿横纹肌肉瘤的横断面成像特征是否与肿瘤的不同病理亚型具有特异性。
回顾性分析了 14 例经病理诊断为横纹肌肉瘤的小儿患者的病历资料。获取了患者的人口统计学信息，包括年龄和性别，以及最终的病理报告。由两名放射科医生对诊断前获得的初始 CT、MRI 或两者进行了回顾性分析。我们记录了肿瘤的特征，包括部位、大小、边界、局部扩展和转移的存在。还记录了肿瘤内的钙化、出血或坏死以及肿瘤的衰减和异质性情况。
我们的 14 例患者中，有 10 例被正式诊断为胚胎型横纹肌肉瘤，3 例为肺泡型，1 例为低分化型。在 CT 上，胚胎型和肺泡型肿瘤的衰减和异质性没有显著差异。
在初始表现时的影像学特征，如衰减和异质性，与小儿横纹肌肉瘤的病理亚型没有相关性。
