Department of Obstetrics and Gynecology, Mayo Clinic, Rochester, MN 55905, USA.
Mayo Clin Proc. 2011 Mar;86(3):229-40. doi: 10.4065/mcp.2010.0794. Epub 2011 Feb 9.
Premenopausal women with a new diagnosis of breast cancer are faced with many challenges. Providing health care for issues such as gynecologic comorbidities, reproductive health concerns, and vasomotor symptom control can be complicated because of the risks of hormone treatments and the adverse effects of adjuvant therapies. It is paramount that health care professionals understand and be knowledgeable about hormonal and nonhormonal treatments and their pharmacological parameters so they can offer appropriate care to women who have breast cancer, with the goal of improving quality of life. Articles for this review were identified by searching the PubMed database with no date limitations. The following search terms were used: abnormal uterine bleeding, physiologic sex steroids, endometrial ablation, hysteroscopic sterilization, fertility preservation in endometrial cancer, tranexamic acid and breast cancer, menorrhagia treatment and breast cancer, abnormal uterine bleeding and premenopausal breast cancer, levonorgestrel IUD and breast cancer, tamoxifen and gynecologic abnormalities, tamoxifen metabolism, hormones and breast cancer risk, contraception and breast cancer, pregnancy and breast cancer, and breast cancer and infertility treatment.
对于新诊断出患有乳腺癌的绝经前女性来说，面临着许多挑战。由于激素治疗的风险和辅助治疗的不良反应，为妇科合并症、生殖健康问题和血管舒缩症状控制等问题提供医疗保健可能会很复杂。医疗保健专业人员了解和熟悉激素和非激素治疗及其药理学参数至关重要，这样他们才能为患有乳腺癌的女性提供适当的护理，以提高生活质量。本文的研究文章是通过在 PubMed 数据库中无时间限制地搜索确定的。使用了以下搜索词：异常子宫出血、生理性激素、子宫内膜消融术、宫腔镜绝育术、子宫内膜癌的生育保存、氨甲环酸和乳腺癌、月经过多治疗和乳腺癌、异常子宫出血和绝经前乳腺癌、左炔诺孕酮宫内节育器和乳腺癌、他莫昔芬和妇科异常、他莫昔芬代谢、激素和乳腺癌风险、避孕和乳腺癌、妊娠和乳腺癌以及乳腺癌和不孕治疗。
