Can Fam Physician. 1977 Jan;23:37-40.
The major area of new drug discoveries for the treatment of arthritis is in non-steroidal anti-inflammatory agents (NSAIA). Unfortunately, as yet no new and safe drug of major significance has appeared. Aspirin still ranks high beside the newcomers. Indomethacin, ibuprofen, naproxen, fenoprofen and tolmetin are described and their roles in therapy are discussed. A further group of older drugs receiving new application in the treatment of arthritis is presented. These include penicillamine and the immunosuppressive drugs. Gold and chloroquin are also discussed to put these agents in their proper perspective.
治疗关节炎的新药研发主要集中在非甾体类抗炎药（NSAIA）上。遗憾的是，至今尚未出现具有重要意义的新型安全药物。阿司匹林仍然与新药并驾齐驱。吲哚美辛、布洛芬、萘普生、芬布芬和托美汀都有介绍，并讨论了它们在治疗中的作用。还介绍了另一组在关节炎治疗中应用新的老药。这些包括青霉胺和免疫抑制剂。金和氯喹也进行了讨论，以便正确看待这些药物。
