Czarny A, Witkowska D, Mulczyk M
Laboratory of Medical Microbiology, Polish Academy of Sciences, Wrocław.
Arch Immunol Ther Exp (Warsz). 1990;38(5-6):353-7.
Outer membrane proteins (OMP) isolated from Shigella flexneri, Escherichia coli, Proteus vulgaris and Salmonella typhimurium were tested for their protective activity. Each OMP preparate given to mice intraperitoneally in a single injection (5 micrograms/per mouse) protected the animals not only in homologous but also in varying intensity in heterologous systems. Evidence was obtained that this nonspecific protection is cell mediated.
对从福氏志贺菌、大肠杆菌、普通变形杆菌和鼠伤寒沙门氏菌中分离出的外膜蛋白(OMP)进行了保护活性测试。将每种OMP制剂以单次注射(每只小鼠5微克)的方式腹腔注射给小鼠,结果表明这些制剂不仅能在同源系统中,还能在不同程度上在异源系统中保护动物。有证据表明这种非特异性保护是由细胞介导的。