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[秘鲁高海拔人群中血脂异常和空腹血糖受损的高发生率]

[High frequency of dyslipidemia and impaired fasting glycemia in a high altitude Peruvian population].

作者信息

Málaga Germán, Zevallos-Palacios Claudia, Lazo María de los Ángeles, Huayanay Carlos

机构信息

Centro de Excelencia de Enfermedades Crónicas, Universidad Peruana Cayetano Heredia, Lima, Perú.

出版信息

Rev Peru Med Exp Salud Publica. 2010 Oct-Dec;27(4):557-61. doi: 10.1590/s1726-46342010000400010.

Abstract

We performed a cross sectional study in Lari (3600 m), a highland rural community from Arequipa, Peru. We evaluated a body mass index (BMI), glycemia and lipid profile in 74 over 18 year persons. The mean age was 51.7 ± 18.0 years, 62.2% were women, mean of BMI was 25.6 ± 3.7. Prevalence of hypercholesterolemia was 40.6%, "low HDL" in 77% of the population (93.5% in women vs 50% in men, p <0.001) and elevated level of LDL was 71.7%. The prevalence of impaired fasting glycemia was 27%. In conclusion, we found high prevalence of impaired fasting glycemia, hypercholesterolemia and especially "low HDL" in high altitude rural natives. These findings must be considered to realize interventions in high altitude populations to avoid future cardiovascular complications.

摘要

我们在秘鲁阿雷基帕的一个高地农村社区拉里(海拔3600米)进行了一项横断面研究。我们评估了74名18岁以上人群的体重指数(BMI)、血糖和血脂情况。平均年龄为51.7±18.0岁,62.2%为女性,BMI平均值为25.6±3.7。高胆固醇血症的患病率为40.6%,77%的人群存在“低高密度脂蛋白”情况(女性为93.5%,男性为50%,p<0.001),低密度脂蛋白水平升高的比例为71.7%。空腹血糖受损的患病率为27%。总之,我们发现高海拔农村原住民中空腹血糖受损、高胆固醇血症尤其是“低高密度脂蛋白”的患病率很高。在高海拔人群中开展干预措施以避免未来心血管并发症时,必须考虑这些发现。

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