CRONICAS Center of Excellence in Chronic Diseases, Universidad Peruana Cayetano Heredia, Lima, Peru.
PLoS One. 2012;7(4):e35127. doi: 10.1371/journal.pone.0035127. Epub 2012 Apr 5.
Although men and women have similar risk factors for cardiovascular disease, many social behaviors in developing countries differ by sex. Rural-to-urban migrants have different cardiovascular risk profiles than rural or urban dwellers. The objective of this study was to evaluate the sex differences with specific cardiovascular risk factors in rural-to-urban migrants.
We used the rural-to-urban migrant group of the PERU MIGRANT cross-sectional study to investigate the sex differences in specific cardiovascular risk factors: obesity, hypertension, metabolic syndrome, as well as exposures of socioeconomic status, acculturation surrogates and behavioral characteristics. Logistic regression analysis was used to characterize strength of association between sex and our outcomes adjusting for potential confounders. The sample of migrants was 589 (mean age 46.5 years) and 52.4% were female. In the adjusted models, women were more likely to be obese (OR=5.97; 95%CI: 3.21-11) and have metabolic syndrome (OR=2.22; 95%CI: 1.39-3.55) than men, explaining the greatest variability for obesity and metabolic syndrome but not for hypertension.
Our results suggest that interventions for CVD in Peru should be sex-specific and address the unique health needs of migrant populations living in urban shantytowns since the risk factors for obesity and metabolic syndrome differ between males and females.
尽管男性和女性患心血管疾病的风险因素相似，但在发展中国家，许多社会行为因性别而异。农村到城市的移民与农村或城市居民的心血管风险特征不同。本研究的目的是评估农村到城市移民中特定心血管风险因素的性别差异。
我们使用 PERU MIGRANT 横断面研究中的农村到城市移民群体，调查特定心血管风险因素（肥胖、高血压、代谢综合征）以及社会经济地位、文化适应替代指标和行为特征方面的性别差异。使用逻辑回归分析来描述性别与我们的结果之间的关联强度，调整潜在混杂因素。移民样本为 589 人（平均年龄 46.5 岁），其中 52.4%为女性。在调整后的模型中，与男性相比，女性更有可能肥胖（OR=5.97；95%CI：3.21-11）和患有代谢综合征（OR=2.22；95%CI：1.39-3.55），这解释了肥胖和代谢综合征最大的变异性，但不能解释高血压。
我们的结果表明，秘鲁的 CVD 干预措施应该是有针对性别的，并且应该针对居住在城市棚户区的移民群体的独特健康需求，因为肥胖和代谢综合征的风险因素在男性和女性之间存在差异。
