Fu Yuan-yuan, Yu Jin-ming, Wang Jia-hong, Wang Jin-song, Sun Yi-hong, Liu Hui-fang, Hu Da-yi
Tongji University School of Medical Science, Shanghai 200092, China.
Zhonghua Xin Xue Guan Bing Za Zhi. 2010 Jun;38(6):562-6.
To investigate the prevalence and percentage of dyslipidemia awareness among overweight and obese residents in Beijing community.
Cross-sectional data of 9786 subjects from capital cholesterol education and intervention program (CCEIP) were analyzed. Participants were divided into 3 groups (Normal, overweight and obese) based on body mass index (BMI). Blood lipid levels were determined from overnight fasting plasma samples. Questionnaires were collected to estimate awareness of dyslipidemia.
(1) Blood lipids levels were positively correlated with BMI (r = 0.17, 0.18, -0.26 and 0.35 between total cholesterol, LDL cholesterol, HDL cholesterol, triglyceride and BMI, respectively, all P < 0.01). (2) Prevalence of dyslipidemia increased in proportion with increase of BMI. The age-standardized prevalence of dyslipidemia of normal, overweight and obese population was 23. 9%, 43.3% and 65.4% in men and 17.9%, 29.2% and 42.3% in women. Dyslipidemia was more frequent in obese men than obese women (65.4% vs. 42.3%, P < 0.01). However, this gender difference decreased gradually with the increase of age. Risk of hypercholesterolemia, high LDL-C, low HDL-C and hypertriglyceridemia in obese men was 1.6, 2.9, 2.4, and 2.7 folders higher than in the normal body weight men and was 1.3, 1.9, 1.7 and 2.1 folders higher in obese women than in normal body weight women. (3) Unexpectedly, the percentage of dyslipidemia awareness in overweight and obese population was not significantly higher than in the normal body weight group (P > 0.05).
The prevalence of dyslipidemia was high while the percentage of dyslipidemia awareness was rather low in obese population. Aggressive intervention should be taken in obese population, especially in the young obese men, to effectively reduce dyslipidemia.
调查北京社区超重和肥胖居民血脂异常的患病率及知晓率。
分析首都胆固醇教育与干预项目(CCEIP)中9786名受试者的横断面数据。根据体重指数(BMI)将参与者分为3组(正常、超重和肥胖)。通过过夜空腹血浆样本测定血脂水平。收集问卷以评估血脂异常的知晓情况。
(1)血脂水平与BMI呈正相关(总胆固醇、低密度脂蛋白胆固醇、高密度脂蛋白胆固醇、甘油三酯与BMI之间的r分别为0.17、0.18、-0.26和0.35,均P<0.01)。(2)血脂异常患病率随BMI增加而升高。正常、超重和肥胖人群血脂异常的年龄标准化患病率在男性中分别为23.9%、43.3%和65.4%,在女性中分别为17.9%、29.2%和42.3%。肥胖男性的血脂异常比肥胖女性更常见(65.4%对42.3%,P<0.01)。然而,这种性别差异随年龄增长逐渐减小。肥胖男性高胆固醇血症、高LDL-C、低HDL-C和高甘油三酯血症的风险分别比正常体重男性高1.6、2.9、2.4和2.7倍,肥胖女性分别比正常体重女性高1.3、1.9、1.7和2.1倍。(3)出乎意料的是,超重和肥胖人群血脂异常的知晓率并不显著高于正常体重组(P>0.05)。
肥胖人群血脂异常患病率高而知晓率低。应对肥胖人群,尤其是年轻肥胖男性采取积极干预措施,以有效降低血脂异常。