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与系统性红斑狼疮相关的泛发性皮肤钙质沉着症:1例严重病例

Calcinosis cutis universalis associated with systemic lupus erythematosus: an exuberant case.

作者信息

Carocha Ana Paula Gonçalves, Torturella Daniel Moscon, Barreto Gimelly Ribeiro, Estrella Rogerio Ribeiro, Rochael Mayra Carrijo

机构信息

Dermatology at the Universidade Federal Fluminense, Niteroi, Rio de Janeiro, Brazil.

出版信息

An Bras Dermatol. 2010 Nov-Dec;85(6):883-7. doi: 10.1590/s0365-05962010000600016.

Abstract

Calcinosis cutis is an uncommon disease of unclear pathophysiology that is often disabling. It is characterized by the formation of calcium deposits in the skin or subcutaneous tissue. It is classified into four subtypes: dystrophic, metastatic, idiopathic or iatrogenic. It may be seen in a variety of systemic diseases such as hyperparathyroidism and hypervitaminosis D, but is most commonly found in dermatomyositis, scleroderma and overlap syndromes and is a rare complication of systemic lupus erythematosus. The management of secondary complications and the success of therapy are constant challenges in the follow-up of these cases.

摘要

皮肤钙化症是一种病理生理学尚不明确的罕见疾病,常导致功能障碍。其特征是在皮肤或皮下组织中形成钙沉积。它分为四种亚型:营养不良性、转移性、特发性或医源性。它可见于多种全身性疾病,如甲状旁腺功能亢进和维生素D过多症,但最常见于皮肌炎、硬皮病和重叠综合征,也是系统性红斑狼疮的罕见并发症。在这些病例的随访中,继发性并发症的处理和治疗的成功一直是挑战。

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