Department of Dermatology, Hospital Universitario de la Princesa, Madrid, Spain.
Lupus. 2010 May;19(6):762-4. doi: 10.1177/0961203309355298. Epub 2010 Feb 15.
Cutaneous calcinosis can be classified into four types: dystrophic, metastatic, idiopathic and iatrogenic. Dystrophic calcification constitutes the most frequent variant and is associated with a large number of illnesses, among which are included some collagen diseases such as CREST syndrome, scleroderma, dermatomyositis and lupus erythematosus. We present a case of dystrophic calcinosis cutis, affecting the fingertip of a woman with a 10-year history of primary Sjögren's syndrome (SS). She has been receiving diltiazem as a treatment for the last 15 months, resulting in the partial resolution of the lesions. We emphasize the fact that the presence of calcinosis cutis has not been described previously in patients with SS, and that diltiazem has partially improved our patient's cutaneous lesions.
营养不良性、转移性、特发性和医源性。营养不良性钙化构成了最常见的变异类型，与许多疾病相关，其中包括一些胶原疾病，如 CREST 综合征、硬皮病、皮肌炎和红斑狼疮。我们报告一例营养不良性皮肤钙化症，影响一位患有原发性干燥综合征（SS） 10 年的女性的指尖。她在过去 15 个月接受地尔硫卓治疗，导致病变部分缓解。我们强调的是，以前在 SS 患者中没有描述过皮肤钙化症的存在，而且地尔硫卓部分改善了我们患者的皮肤病变。
