Bedioui Heykal, Daghfous Amine, Baraket Oussama, Chouaieb Sofiene, Kallel Lamia, Ayadi Sofiene, Noomen Rabii, Chebbi Faouzi, Ksantini Rachid, Jouini Mohamed, Kacem Montacer, Ben Safta Zoubeir
Universite Tunis, El Manar, Tunisie.
Tunis Med. 2011 Feb;89(2):198-201.
An uncommon event in the natural course of Crohn's disease is the spontaneous perforation. It's the most serious intestinal complication.
To report the incidence of this complication and to discuss the mechanism of the perforation.
We report, retrospectively, 4 cases (3 men and one woman; median age: 30 years) of peritonitis complicating Crohn's disease and study their clinical characteristics intra operatively findings and course evolution. Steroid therapy was administrated to all patients before the perforation. The perforation sites are on the ileum in three cases and on the jejunum in one case. The treatment consists in a resection of the perforated intestine with stoma in all cases.
Perforation in Crohn's disease is a rare event. The exact mechanism of the perforation is still unknown and many hypotheses are presented.
克罗恩病自然病程中一种不常见的事件是自发性穿孔。它是最严重的肠道并发症。
报告这种并发症的发生率并讨论穿孔机制。
我们回顾性报告4例（3名男性和1名女性；中位年龄：30岁）并发克罗恩病的腹膜炎病例，并研究其临床特征、术中发现及病程演变。所有患者在穿孔前均接受了类固醇治疗。穿孔部位3例在回肠，1例在空肠。所有病例的治疗均包括切除穿孔肠段并行造口术。
克罗恩病穿孔是一种罕见事件。穿孔的确切机制仍不清楚，目前有多种假说。
